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The Safe Use of Analgesics in Patients with Cirrhosis: A Narrative Review.

Author: BjörnssonEinar Stefán, ChalasaniNaga, MaJiayi

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cirrhosis can significantly impact drug metabolism and increase the risk of adverse effects. This review provides guidance for choosing appropriate analgesics for patients with cirrhosis. Acetaminophen remains the preferred analgesic, while non-selective nonsteroidal anti-inflammatory drugs should generally be avoided. Opioids should be used cautiously due to the risk of hepatic encephalopathy.
Paper Details　
Original Abstract of the Article :
Pain is prevalent in patients with cirrhosis. Due to potential alterations in drug metabolism, risk for adverse effects, and complications from cirrhosis, physicians are often faced with difficult choices when choosing appropriate analgesics in these patients. Overall, acetaminophen remains the pref...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjmed.2023.10.022

データ提供：米国国立医学図書館（NLM）

Navigating the Painful Desert of Cirrhosis

Cirrhosis, a chronic liver disease, can feel like a vast and unforgiving desert, filled with discomfort and challenges. This review focuses on the safe use of analgesics in patients with cirrhosis, a topic of paramount importance considering the potential complications and drug interactions associated with this condition.

The authors emphasize that acetaminophen remains the preferred analgesic for patients with cirrhosis, due to its relative safety and effectiveness. They also provide guidance on the use of other pain medications, highlighting the potential risks and benefits associated with each. This information is like a desert guide, helping healthcare professionals navigate the challenging terrain of pain management in patients with cirrhosis.

The review covers a range of analgesics, including non-selective nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, and gabapentinoids. It provides specific recommendations on which medications to avoid and which to use with caution, considering the unique needs and vulnerabilities of patients with cirrhosis.

A Pathway to Pain Relief

This review offers valuable guidance for healthcare professionals, providing evidence-based recommendations on the safe use of analgesics in patients with cirrhosis. It's like discovering a map through the desert, highlighting safe pathways to pain relief and minimizing the risks associated with certain medications.

A Journey Towards Better Pain Management

This review underscores the importance of careful consideration when choosing analgesics for patients with cirrhosis, emphasizing the need to prioritize safety and effectiveness. It provides a framework for navigating the challenges of pain management in this complex patient population, allowing healthcare professionals to make informed decisions that prioritize the well-being of their patients.

Dr. Camel's Conclusion

This narrative review provides a comprehensive overview of the safe use of analgesics in patients with cirrhosis. It offers valuable guidance for healthcare professionals, emphasizing the importance of considering the unique needs and vulnerabilities of this patient population when choosing pain medications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-01
Further Info :

Pubmed ID

37918778

DOI: Digital Object Identifier

10.1016/j.amjmed.2023.10.022

SNS
PICO Info
in preparation
Languages

English

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