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Relative efficacy of maintenance therapy with theophylline, inhaled albuterol, and the combination for chronic asthma.

Author: AhrensR C, JoadJ P, LindgrenS D, WeinbergerM M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Theophylline and a combination of theophylline and albuterol were more effective than albuterol alone in reducing asthma symptoms. The study showed that albuterol had a shorter duration of action, which may limit its effectiveness for managing nocturnal symptoms.
Paper Details　
Original Abstract of the Article :
The relative benefit of maintenance therapy with theophylline, inhaled albuterol, and the combination was examined in 18 adolescents and adults with chronic asthma during a 3-month, randomized, double-blind, crossover trial. Theophylline and combination regimens were associated with significantly fe...See full text at original site
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引用元：
https://doi.org/10.1016/s0091-6749(87)80020-9

データ提供：米国国立医学図書館（NLM）

Theophylline, Albuterol, or Combo for Chronic Asthma: A Desert of Choices

Imagine asthma as a desert oasis, where the air can shift from calm to turbulent in an instant. This study explores the effectiveness of different maintenance therapies for chronic asthma – theophylline, inhaled albuterol, and a combination of both. The research aims to determine which strategy provides the best protection against asthma symptoms, particularly those experienced at night.

Theophylline and Combo: A More Stable Desert Oasis

The study found that theophylline and the combination therapy were more effective in reducing asthma symptoms compared to albuterol alone. This suggests that theophylline and the combination therapy provide a more consistent and stable environment in the desert oasis of asthma, minimizing the risk of unexpected symptom flares. The study also found that albuterol's effectiveness was more transient, highlighting the need for a more sustained approach to asthma management, particularly during nighttime hours.

Navigating Asthma: A Journey of Personalized Care

This study emphasizes the importance of finding the right treatment strategy for individual patients. It suggests that theophylline and combination therapies might be particularly beneficial for those with nocturnal asthma symptoms, offering a more stable and predictable environment in the oasis of asthma. This research highlights the need for personalized care and a tailored approach to asthma management.

Dr.Camel's Conclusion

This study reminds us that there’s no one-size-fits-all solution in the desert oasis of asthma management. It underscores the importance of finding the right treatment strategy for individual patients, ensuring a more stable and comfortable journey. The study also highlights the importance of a multi-faceted approach to asthma management, considering both acute and long-term symptom control.

Date :
  1. Date Completed 1987-03-17
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

3805550

DOI: Digital Object Identifier

10.1016/s0091-6749(87)80020-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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