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Current status and prospects for oral acyclovir treatment of first episode and recurrent genital herpes simplex virus.

Author: BrysonY J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral acyclovir was found to be effective in treating both primary and recurrent genital herpes, significantly reducing viral shedding, lesion formation, and symptom duration compared to placebo.
Paper Details　
Original Abstract of the Article :
Herpes simplex genitalis is an increasingly common primary or recurrent HSV infection. Acyclovir (ACV) has been found to diminish virus shedding and clinical symptoms in patients with first episode genital HSV when given topically or intravenously. As most patients with first episode disease do not ...See full text at original site
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引用元：
https://doi.org/10.1093/jac/12.suppl_b.61

データ提供：米国国立医学図書館（NLM）

Oral Acyclovir: A Powerful Oasis in the Desert of Herpes Simplex Virus

Herpes simplex virus (HSV) infections, like persistent desert sandstorms, can cause recurrent outbreaks and significant discomfort. This review explores the efficacy of oral acyclovir (ACV) for the treatment of both first episode and recurrent genital HSV infections.

Oral Acyclovir: A Proven Treatment?

Studies have demonstrated that oral ACV is effective in reducing virus shedding, lesion formation, and symptom duration in patients with both first episode and recurrent genital HSV infections. The results, like finding a refreshing spring in the desert, suggest that oral ACV may be a valuable treatment option for managing HSV infections.

Health Implications and Application

These findings, like a beacon of hope in the desert of HSV infections, highlight the importance of early and effective antiviral therapy for managing HSV infections. This review encourages self-initiated treatment during the prodromal period or early in a recurrence, emphasizing the importance of patient education and proactive management of HSV infections.

Dr.Camel's Conclusion

The desert of HSV infections can be a challenging place, filled with discomfort and recurrent outbreaks. This review sheds light on the effectiveness of oral ACV as a valuable treatment option for managing these infections. However, the desert of medical research is vast, and we must continue to explore new avenues for prevention and treatment, including vaccine development, to ultimately conquer this persistent viral foe.

Date :
  1. Date Completed 1983-12-20
  2. Date Revised 2019-05-11
Further Info :

Pubmed ID

6355052

DOI: Digital Object Identifier

10.1093/jac/12.suppl_b.61

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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