Paper Details

  1. Home
  2. Paper Details

Double-blind comparison of acute effects of inhaled albuterol, isoproterenol and placebo on cardiopulmonary function and gas exchange in asthmatic children.

Author: KatzR, LittnerM R, SiegelS C, TashkinD P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Albuterol aerosol was effective in treating 11 asthmatic children. It caused bronchodilation for up to six hours. No significant adverse effects were observed.
Paper Details　
Original Abstract of the Article :
Although albuterol aerosol is an effective bronchodilator in adult asthmatics its efficacy and safety are not fully established in asthmatic children. Albuterol (100 and 200 micrograms), isoproterenol (70 and 140 micrograms) and placebo were administered from metered dose aerosol cannisters to 11 as...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/6846920

データ提供：米国国立医学図書館（NLM）

Double-Blind Comparison of Acute Effects of Inhaled Albuterol, Isoproterenol, and Placebo on Cardiopulmonary Function and Gas Exchange in Asthmatic Children

In the realm of pediatric asthma, inhaled bronchodilators play a critical role in providing relief from the debilitating symptoms of this chronic respiratory condition. This study, a double-blind comparison, focuses on the acute effects of inhaled albuterol and isoproterenol, two commonly used bronchodilators, on the cardiopulmonary function and gas exchange of asthmatic children. The researchers meticulously evaluated the effectiveness of these medications, seeking to determine their impact on lung function and overall well-being.

Inhaled Bronchodilators: A Lifesaver for Asthmatic Children

The study's findings demonstrated that inhaled albuterol was an effective bronchodilator for asthmatic children, providing significant relief from airway constriction and improving lung function. The results also indicated that albuterol was more effective than comparable doses of isoproterenol, highlighting its potential as a preferred bronchodilator for children with asthma.

Providing Relief from the Symptoms of Asthma

The desert of asthma can be a difficult and uncomfortable place for children, but this study offers a beacon of hope. By understanding the effectiveness of inhaled bronchodilators like albuterol, we can provide children with asthma the relief they need to breathe easier and live fuller lives. Think of these medications as a cool oasis in the desert, offering respite from the symptoms of asthma.

Dr.Camel's Conclusion

This study highlights the importance of inhaled bronchodilators in the management of asthma in children. The findings provide valuable insights into the effectiveness and safety of these medications, guiding clinicians towards the most appropriate treatment options for their young patients. Think of this research as a compass, guiding us towards a brighter future for children with asthma.

Date :
  1. Date Completed 1983-06-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6846920

DOI: Digital Object Identifier

6846920

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.