Changes in single symptoms and separate factors of the schizophrenic syndrome after treatment with risperidone or haloperidol.

Author: LindströmE, von KnorringL

Paper Details 
Original Abstract of the Article :
Risperidone, a rather selective blocker of D-2 and 5-HT-2 receptors, was, in the doses 1 mg, 4 mg, 8 mg, 12 mg and 16 mg a day, compared to the rather selective D-2 blocker haloperidol in the dose of 10 mg a day, in 88 chronic schizophrenic patients. After one week placebo wash-out, the patients wer...See full text at original site
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引用元:
https://doi.org/10.1055/s-2007-1014288

データ提供:米国国立医学図書館(NLM)

A Tale of Two Drugs: Comparing Risperidone and Haloperidol in Schizophrenia Treatment

This research explores the effectiveness of two [antipsychotic medications], [risperidone] and [haloperidol], in treating [chronic schizophrenia]. The researchers, embarking on a double-blind parallel-group study, compared the effects of these drugs on various aspects of the [schizophrenic syndrome]. This research is a valuable contribution to our understanding of [antipsychotic treatment] and its impact on patients with schizophrenia.

Finding the Right Dose: Risperidone and its Curvilinear Dose-Response Curve

The researchers found that [risperidone] had a [curvilinear dose-response curve], with an optimal effect at a dose of [4 mg per day] for [negative, anxious/depressive, and cognitive factors] and [8 mg per day] for [positive and excited factors]. This finding suggests that [risperidone] may be more effective than [haloperidol] in treating specific aspects of the [schizophrenic syndrome] when administered at the right dose. This research underscores the importance of individualized dosing in [antipsychotic treatment] to optimize patient outcomes.

A New Era in Schizophrenia Treatment: The Potential of Risperidone

This research offers a promising new avenue for [schizophrenia treatment]. The researchers found that [risperidone] had significant effects on all five factors of the [schizophrenic syndrome], including [cognitive function], which is particularly important for [rehabilitation]. This research is a testament to the ongoing evolution of [antipsychotic medication] and its potential to improve the lives of people with schizophrenia. The findings encourage further research into the specific effects of [risperidone] on different aspects of the [schizophrenic syndrome] and its potential to improve cognitive function.

Dr.Camel's Conclusion

This research, like a well-traveled path through the desert of schizophrenia treatment, offers a deeper understanding of the effectiveness of risperidone and haloperidol. The study highlights the importance of finding the right dose for each patient and emphasizes the potential of risperidone to improve cognitive function. It's a reminder that in the vast and complex landscape of mental health treatment, we must continue to explore new options and strive for better outcomes for those who need it most.

Date :
  1. Date Completed 1994-10-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7521534

DOI: Digital Object Identifier

10.1055/s-2007-1014288

SNS
PICO Info
in preparation
Languages

English

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