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Side effects of iron supplements in blood donors: superior tolerance of heme iron.

Author: BystromM, EdbergA, FrykmanE, HansenT, JanssonU

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study compared the side effects of two iron supplements: one with both heme and non-heme iron (Hemofer), and one with only non-heme iron (Erco-Fer). While both were equally effective in replenishing iron levels, Hemofer resulted in significantly fewer side effects, including constipation, compared to Erco-Fer and a placebo.
Paper Details　
Original Abstract of the Article :
Regular blood donors were enrolled in a double-blind, parallel group study to evaluate the side effects of two iron supplements, one containing both heme iron and non-heme iron (Hemofer, 2 tablets = 18 mg iron/day), the other non-heme iron only (Erco-Fer; 1 tablet = 60 mg iron/day). No differences w...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8145004

データ提供：米国国立医学図書館（NLM）

Iron Supplementation: A Balancing Act Between Efficacy and Side Effects

Iron deficiency is a common concern, especially among blood donors. This study explores the impact of different iron supplements on blood donors, comparing the side-effect profiles of heme iron and non-heme iron supplements. The researchers aim to identify the best approach to restoring iron levels while minimizing the risk of undesirable side effects.

Heme Iron: A More Tolerable Option for Iron Supplementation

The study found that a low-dose iron supplement containing both heme iron and non-heme iron resulted in significantly fewer side effects, particularly constipation, compared to a traditional non-heme iron supplement. These findings suggest that heme iron supplements may offer a more tolerable option for individuals seeking to restore iron levels.

Navigating the Iron Supplementation Landscape

The research highlights the importance of choosing iron supplements carefully, considering both efficacy and side effects. Patients should consult with their healthcare providers to determine the most appropriate iron supplement for their individual needs.

Dr. Camel's Conclusion

This study is like a journey through an iron-rich desert, where we discover that heme iron supplements offer a smoother path to restoring iron levels with fewer side effects. While both heme and non-heme iron supplements are effective in restoring iron status, the study suggests that heme iron may be a more tolerable option for those seeking to avoid unwanted side effects.

Date :
  1. Date Completed 1994-05-05
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

8145004

DOI: Digital Object Identifier

8145004

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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