Double-masked comparative study of UF-021 and timolol ophthalmic solutions in patients with primary open-angle glaucoma or ocular hypertension.

Author: AzumaI, KitazawaY, MasudaK, TakaseM, YamamuraH

Paper Details 
Original Abstract of the Article :
A double-masked comparative clinical study of UF-021 (Rescula), a unique prostaglandin-related compound, was carried out at 18 centers with timolol maleate 0.5% ophthalmic solution as an active reference drug. After a wash-out period, UF-021 (0.12%) or timolol (0.5%) was given topically twice a day ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8145398

データ提供:米国国立医学図書館(NLM)

UF-021 vs. Timolol: A Double-Masked Comparative Study in Glaucoma

The world of ophthalmology is a vast and intricate desert, with countless conditions affecting the delicate structures of the eye. This research explores the efficacy and safety of UF-021 (Rescula), a unique prostaglandin-related compound, in treating primary open-angle glaucoma or ocular hypertension. The study meticulously compared UF-021 with timolol maleate 0.5% ophthalmic solution, a well-established reference drug, through a double-masked, randomized, controlled clinical trial. It's like comparing two different oases within the desert, seeking the most effective solution for a common eye condition.

UF-021: A Promising Alternative

The researchers found that UF-021 effectively lowered intraocular pressure, demonstrating its potential as a viable alternative to timolol. They observed a similar level of effectiveness in both groups, but UF-021 did not have a significant impact on blood pressure, which is a potential concern with timolol.

Minimizing Side Effects and Maintaining Well-being

This research suggests that UF-021 may offer a valuable alternative for patients with glaucoma or ocular hypertension, minimizing potential cardiovascular side effects. It emphasizes the importance of exploring diverse treatment options to optimize patient outcomes and maintain overall well-being.

Dr.Camel's Conclusion

This research sheds light on a promising new oasis within the desert of glaucoma treatment, offering a potential alternative to traditional therapies with fewer cardiovascular side effects. UF-021 stands as a testament to the ongoing search for effective and well-tolerated treatments for glaucoma, a condition affecting millions worldwide. It's a reminder that the desert of ophthalmology holds countless surprises, and continuous research is essential to improve patient care.

Date :
  1. Date Completed 1994-05-02
  2. Date Revised 2016-11-23
Further Info :

Pubmed ID

8145398

DOI: Digital Object Identifier

8145398

SNS
PICO Info
in preparation
Languages

English

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