Decrease of histamine induced bronchoconstriction by caffeine in mild asthma.

Author: FullerR W, HendersonJ C, O'ConnellF

Paper Details 
Original Abstract of the Article :
While high doses of caffeine may affect pulmonary function and bronchial challenge tests in patients with mild asthma, the effects of lower doses (< or = 5 mg/kg) are less well documented. Specific recommendations exist for withholding theophylline, but not caffeine, before bronchoprovocation and pu...See full text at original site
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引用元:
https://doi.org/10.1136/thx.48.8.824

データ提供:米国国立医学図書館(NLM)

Caffeine: A Potential Ally Against Bronchoconstriction in Mild Asthma

Asthma is a chronic respiratory condition that can cause significant airway narrowing, leading to breathing difficulties. This research investigates the effects of caffeine on histamine-induced bronchoconstriction in patients with mild asthma.

Caffeine's Impact on Bronchoconstriction in Mild Asthma

The study found that low doses of caffeine (≤5 mg/kg) significantly reduced histamine-induced bronchoconstriction in patients with mild asthma. The authors concluded that caffeine, at these lower doses, might have a protective effect against airway narrowing in mild asthma. This finding suggests that caffeine could be a potential therapeutic option for managing bronchoconstriction in mild asthma.

Exploring Caffeine's Role in Asthma Management

This research provides valuable insights into the potential role of caffeine in asthma management. The findings suggest that low-dose caffeine might offer a safe and effective way to mitigate bronchoconstriction in mild asthma. However, further research is needed to confirm these findings and to establish optimal dosages and long-term efficacy.

Dr.Camel's Conclusion

Imagine asthma as a desert sandstorm that makes breathing difficult. This research explores the concept of using caffeine, like a desert wind, to help clear the airways and make breathing easier. The findings suggest that caffeine might be a valuable tool in managing asthma symptoms, reminding us that even familiar substances can have surprising therapeutic benefits.

Date :
  1. Date Completed 1993-11-08
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

8211873

DOI: Digital Object Identifier

10.1136/thx.48.8.824

SNS
PICO Info
in preparation
Languages

English

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