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Computerized task battery assessment of cognitive and performance effects of acute phenytoin motion sickness therapy.

Author: AhmedN, ChelenW, KabriskyM, RogersS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Phenytoin is a drug that is used to treat seizures. This study found that phenytoin, when used at levels that are effective for treating motion sickness, did not have any significant negative effects on cognitive function or performance.
Paper Details　
Original Abstract of the Article :
Phenytoin was previously evaluated as an efficacious anti-motion sickness therapy in more than 24 individuals. To be effective, this short-term, novel therapy requires serum levels in the anticonvulsant range; therefore, it became imperative that the effects of phenytoin upon cognition and performan...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://pubmed.ncbi.nlm.nih.gov/8447800

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Motion Sickness

Motion sickness can leave individuals feeling disoriented and distressed, like a camel lost in a swirling sandstorm. This study investigates the potential of phenytoin, a drug typically used to treat seizures, as a treatment for motion sickness.

A New Approach to a Familiar Problem

The researchers found that phenytoin was effective in treating motion sickness in individuals with serum levels within the anticonvulsant range. They also observed that, despite subjective side effects reported by individuals with higher serum levels, phenytoin did not significantly impair cognitive function or performance. This study suggests that phenytoin could be a viable alternative for individuals struggling with motion sickness.

Finding Calm in the Storm

This research offers a glimmer of hope for individuals struggling with motion sickness, highlighting the potential of phenytoin as a novel treatment option. It suggests that with careful monitoring, phenytoin may provide relief from the distressing symptoms of motion sickness.

Dr.Camel's Conclusion

Just as a camel needs a sturdy guide to navigate the shifting sands of the desert, individuals experiencing motion sickness may benefit from the guidance of a new treatment option like phenytoin. This research offers a ray of hope for finding calm amidst the storm of motion sickness.

Date :
  1. Date Completed 1993-04-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8447800

DOI: Digital Object Identifier

8447800

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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