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Transplantation of bone marrow and peripheral stem cells.

Author: AlvegårdT

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

A review of 59 studies found that whole-body radiation therapy is used in bone marrow transplantation, but treatment approaches vary widely. Both single-dose and fractionated radiation seem equally effective when delivered optimally. Single-dose radiation may lead to a higher risk of cataracts, while fractionated treatment requires more resources but is less demanding for patients. For advanced leukemia and certain other cancers, a combination of high-dose medication and radiation is likely better than medication alone. For less advanced cancers, different preparation methods for bone marrow transplantation appear to be equally effective.
Paper Details　
Original Abstract of the Article :
This synthesis of the literature on radiotherapy related to bone marrow transplantation is based on 59 scientific articles, including 5 randomized studies and 20 retrospective studies. These studies involve 2563 patients. Bone marrow transplantation is a rapidly expanding treatment method where whol...See full text at original site
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引用元：
https://doi.org/10.3109/02841869609101674

データ提供：米国国立医学図書館（NLM）

The Shifting Sands of Bone Marrow Transplantation: A Review

Bone marrow transplantation, a transformative treatment for various hematological malignancies, is like a journey through a vast and dynamic desert. This article reviews the literature on radiotherapy related to bone marrow transplantation, exploring the different approaches and their outcomes. The authors delve into the complexities of this treatment, seeking to understand the best strategies for achieving successful transplantation.

Radiotherapy in Bone Marrow Transplantation: Navigating the Desert

This article examines the role of radiotherapy in bone marrow transplantation, highlighting the various approaches, including fractionated and single-dose whole-body irradiation. The authors explore the potential benefits and risks associated with each approach, seeking to identify the most effective and safe strategies for conditioning patients before transplantation.

Navigating the Landscape of Hematological Treatment

The treatment of hematological malignancies is a complex and evolving field. This article underscores the importance of careful consideration and individualized treatment plans in bone marrow transplantation. The authors highlight the need for ongoing research to optimize treatment strategies and enhance the effectiveness of this life-saving procedure.

Dr. Camel's Conclusion

This review is like a camel caravan traversing the vast and ever-changing landscape of bone marrow transplantation. The researchers explore the intricacies of radiotherapy, seeking to find the best path to success in this life-saving procedure. Their insights highlight the importance of understanding the nuances of this treatment approach and the need for ongoing research to further optimize its effectiveness.
Date :
  1. Date Completed 1997-06-11
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

9154106

DOI: Digital Object Identifier

10.3109/02841869609101674

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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