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Comparison of amlodipine and long-acting diltiazem in the treatment of mild or moderate hypertension.

Author: CleggL, HorwitzL D, WeinbergerH D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Amlodipine was found to be more effective than diltiazem in reducing systolic and diastolic blood pressure in 123 patients with diastolic blood pressures ranging from 95 to 114 mm Hg before treatment. Both drugs were well-tolerated and reduced blood pressures consistently over the 10-week test period.
Paper Details　
Original Abstract of the Article :
The comparative effects of the once a day calcium channel antagonists amlodipine and long-acting diltiazem were assessed in a parallel design, investigator-blinded, multicenter trial in 123 patients with diastolic blood pressures ranging from 95 to 114 mm Hg before treatment. Patients were randomize...See full text at original site
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引用元：
https://doi.org/10.1016/s0895-7061(97)00264-1

データ提供：米国国立医学図書館（NLM）

Comparing Amlodipine and Diltiazem for Mild to Moderate Hypertension

High blood pressure is a significant health concern. This research compared the effectiveness of two calcium channel blockers, [amlodipine and diltiazem], for treating mild to moderate hypertension. They conducted a multicenter study involving over 100 patients, measuring blood pressure before and after treatment with each medication.

Amlodipine Shows Superior Blood Pressure Reduction

The study found that both medications reduced blood pressure effectively, but [amlodipine was more effective than diltiazem] in lowering both systolic and diastolic blood pressure across a range of doses. It’s like finding a shortcut through the desert, leading to faster and more efficient results.

Navigating High Blood Pressure Treatment

Hypertension requires careful management. This research adds to our understanding of treatment options and their effectiveness. Finding the right medication and dose can be like finding the perfect path in the desert, one that leads to sustainable health and well-being.

Dr. Camel's Conclusion

This study provides valuable information for clinicians treating hypertension. The findings suggest that amlodipine may be a more effective option than diltiazem for achieving optimal blood pressure control. It’s important to work with a healthcare professional to determine the best treatment plan based on individual needs and preferences.

Date :
  1. Date Completed 1998-01-09
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

9397246

DOI: Digital Object Identifier

10.1016/s0895-7061(97)00264-1

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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