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Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome.

Author: BallP, BreierA, BuchananR W, CarpenterW T, KirkpatrickB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study investigated the effectiveness of clozapine for treating both positive and negative symptoms of schizophrenia, including those with and without the deficit syndrome. The researchers also looked at the long-term effects of clozapine on various aspects of the illness, including social and occupational functioning, and quality of life.
Paper Details　
Original Abstract of the Article :
In a preliminary report, the authors observed that clozapine was superior to haloperidol in the treatment of positive and negative symptoms in stable outpatients with schizophrenia. In this final report, they examine the effects of clozapine on positive and negative symptoms in patients with and wit...See full text at original site
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引用元：
https://doi.org/10.1176/ajp.155.6.751

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1998-06-18
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

9619146

DOI: Digital Object Identifier

10.1176/ajp.155.6.751

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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