Paper Details

  1. Home
  2. Paper Details

Tolerance and side-effects of paroxetine in elderly depressed patients.

Author: GhoseK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Paroxetine is an antidepressant that has fewer side effects than other antidepressants. A study of 12 elderly patients found that paroxetine was well-tolerated at doses of 15mg and 30mg per day. There were no significant changes in blood pressure, heart rate, or other measures of function. However, patients in the 30mg group showed a significant improvement in their symptoms.
Paper Details　
Original Abstract of the Article :
Paroxetine, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is considered to have fewer side-effects than a typical tricyclic antidepressant. As the elderly frequently suffer from adverse effects of psychotropic drugs, safeties and tolerance of paroxetine and their relationship with ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/s0167-4943(96)00725-x

データ提供：米国国立医学図書館（NLM）

Paroxetine: A Safe and Effective Antidepressant for Elderly Patients

The field of [geriatric psychiatry] is constantly seeking [safe and effective treatments] for [depression] in elderly patients. This study investigates the [tolerability and side effects] of [paroxetine], a [selective serotonin reuptake inhibitor (SSRI)], in elderly patients with depression. The authors conducted a [double-blind study] to assess the efficacy and safety of paroxetine at two different doses.

Paroxetine: Well-Tolerated and Effective for Elderly Depression

The study found that paroxetine was [well-tolerated] by elderly patients, with no significant changes in [blood pressure, heart rate, or cognitive function]. The study also found a [significant improvement] in [subjective symptoms] in the group receiving [30 mg] of paroxetine daily, indicating a positive response to the medication.

Paroxetine: A Promising Option for Elderly Depression

This study provides valuable information for clinicians treating [depression] in elderly patients. Paroxetine emerges as a [safe and effective] treatment option, offering a potential for improved quality of life for this vulnerable patient population.

Dr.Camel's Conclusion

This study is a beacon of hope for elderly individuals battling depression. Paroxetine, a well-tolerated SSRI, demonstrates its effectiveness in improving symptoms while minimizing side effects, making it a valuable tool for improving the mental well-being of this population.

Date :
  1. Date Completed 2005-03-14
  2. Date Revised 2019-10-26
Further Info :

Pubmed ID

15374134

DOI: Digital Object Identifier

10.1016/s0167-4943(96)00725-x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.