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Specific gel-cream as adjuvant to oral isotretinoin improved hydration and prevented TEWL increase--a double-blind, randomized, placebo-controlled study.
Author: De PabloCarolina, EspadasMaria José, FuenzalidaHéctor, HeraneMaría Isabel, MartinGuillermo González, MiradaAlfons, TrullásCarles, ZegpiEmilia
Original Abstract of the Article :
BACKGROUND: Hydrating and emollient products are often recommended to patients under isotretinoin therapy to control the most frequent mucocutaneous side effects and to improve adherence to treatment. AIMS: To assess, using noninvasive biophysical tests, the clinical and instrumental effectiveness ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1473-2165.2009.00455.x
データ提供:米国国立医学図書館(NLM)
Keeping Your Skin Hydrated During Isotretinoin Therapy
We’re all familiar with the importance of keeping our skin hydrated, especially in the desert. But what about when we’re taking medications that can dry out our skin? This is where the research on isotretinoin comes in. Isotretinoin is a common treatment for acne, but it can sometimes cause dryness and irritation. This study focused on how a special gel-cream might help keep the skin hydrated while using isotretinoin, much like how we use camel milk to stay hydrated in the desert. They compared the gel-cream to a placebo, and the results were clear - the gel-cream helped keep the skin hydrated and reduced acne lesions.
The Gel-Cream’s Impact on Skin Hydration
The study found that the gel-cream significantly improved skin hydration compared to the placebo, and it also prevented the skin from losing too much moisture. This is important because dry skin can be a major source of irritation and discomfort, and it can even lead to worsening acne.
A Smoother Journey Through Acne Treatment
These findings suggest that using a hydrating gel-cream as an adjunct to isotretinoin could make the treatment process more comfortable for patients. It could also help to improve treatment adherence, as patients are less likely to discontinue treatment if their skin is not dry and irritated. This is great news for anyone facing the challenges of acne, much like a camel facing the challenges of the desert!
Dr.Camel's Conclusion
This study highlights the importance of considering the potential side effects of medications like isotretinoin, and how we can work to mitigate those effects. Just as a camel needs to stay hydrated in the desert, people using isotretinoin may benefit from using a hydrating gel-cream to make the journey smoother.
Date :
- Date Completed 2010-01-08
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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