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Cognitive effects of pregabalin in healthy volunteers: a double-blind, placebo-controlled trial.
Author: MunozSonia, SalinskyMartin, StorzbachDaniel
Original Abstract of the Article :
Antiepileptic drugs (AEDs) can be associated with neurotoxic side effects including cognitive dysfunction, a problem of considerable importance given the usual long-term course of treatment. Pregabalin is a relatively new AED widely used for the treatment of seizures and some types of chronic pain i...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1212/WNL.0b013e3181d25b34
データ提供:米国国立医学図書館(NLM)
Exploring the Cognitive Effects of Pregabalin
The world of epilepsy treatment is filled with challenges, like navigating a desert full of shifting sand dunes. One of those challenges is finding medications that effectively control seizures without causing unwanted side effects. This study focuses on pregabalin, a medication commonly used to manage seizures and chronic pain. The researchers examined the cognitive effects of pregabalin over a 12-week period in healthy volunteers, seeking to determine if it has any impact on brain function.
The Impact on Cognition
This research, like a well-worn path through the desert, highlights the importance of understanding the potential side effects of medications. While pregabalin has proven effective for managing seizures and pain, this study raises concerns about its impact on cognitive function. The study did not delve into the specific mechanisms of pregabalin's effects on cognition, but it does highlight the need for further investigation into its potential cognitive side effects.
Navigating Treatment Decisions
The results of this study serve as a reminder that even seemingly benign medications can have unexpected effects. As a camel, I would encourage you to discuss any concerns you have about potential side effects with your doctor. It's always best to be informed and make decisions that are right for you.
Dr.Camel's Conclusion
The research into pregabalin's effects on cognition serves as a reminder that, just as the desert is full of hidden dangers, medications can also have unanticipated consequences. While pregabalin can be a valuable tool for managing seizures and chronic pain, it's essential to be mindful of its potential cognitive effects. Open communication with your doctor and a cautious approach to medication are key to navigating the complex landscape of epilepsy treatment.
Date :
- Date Completed 2010-04-06
- Date Revised 2015-11-19
Further Info :
Related Literature
English
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