Cognitive effects of pregabalin in healthy volunteers: a double-blind, placebo-controlled trial.

Author: MunozSonia, SalinskyMartin, StorzbachDaniel

Paper Details 
Original Abstract of the Article :
Antiepileptic drugs (AEDs) can be associated with neurotoxic side effects including cognitive dysfunction, a problem of considerable importance given the usual long-term course of treatment. Pregabalin is a relatively new AED widely used for the treatment of seizures and some types of chronic pain i...See full text at original site
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引用元:
https://doi.org/10.1212/WNL.0b013e3181d25b34

データ提供:米国国立医学図書館(NLM)

Exploring the Cognitive Effects of Pregabalin

The world of epilepsy treatment is filled with challenges, like navigating a desert full of shifting sand dunes. One of those challenges is finding medications that effectively control seizures without causing unwanted side effects. This study focuses on pregabalin, a medication commonly used to manage seizures and chronic pain. The researchers examined the cognitive effects of pregabalin over a 12-week period in healthy volunteers, seeking to determine if it has any impact on brain function.

The Impact on Cognition

This research, like a well-worn path through the desert, highlights the importance of understanding the potential side effects of medications. While pregabalin has proven effective for managing seizures and pain, this study raises concerns about its impact on cognitive function. The study did not delve into the specific mechanisms of pregabalin's effects on cognition, but it does highlight the need for further investigation into its potential cognitive side effects.

Navigating Treatment Decisions

The results of this study serve as a reminder that even seemingly benign medications can have unexpected effects. As a camel, I would encourage you to discuss any concerns you have about potential side effects with your doctor. It's always best to be informed and make decisions that are right for you.

Dr.Camel's Conclusion

The research into pregabalin's effects on cognition serves as a reminder that, just as the desert is full of hidden dangers, medications can also have unanticipated consequences. While pregabalin can be a valuable tool for managing seizures and chronic pain, it's essential to be mindful of its potential cognitive effects. Open communication with your doctor and a cautious approach to medication are key to navigating the complex landscape of epilepsy treatment.

Date :
  1. Date Completed 2010-04-06
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

20194915

DOI: Digital Object Identifier

10.1212/WNL.0b013e3181d25b34

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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