Comparison of the efficacy and side effects of aqueous steroid nasal spray (budesonide) and allergen-injection therapy (Pollinex-R) in the treatment of seasonal allergic rhinoconjunctivitis.

Author: HargreaveF E, JuniperE F, KlineP A, RamsdaleE H

Paper Details 
Original Abstract of the Article :
The efficacy and side effects of two approaches to the treatment of ragweed pollen-induced rhinoconjunctivitis were compared in a double-blind, parallel-group trial. Sixty ragweed-sensitive adults were randomized either to a course of four Pollinex-R hyposensitization injections during the 6 weeks b...See full text at original site
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引用元:
https://doi.org/10.1016/0091-6749(90)90100-i

データ提供:米国国立医学図書館(NLM)

Comparing the Effectiveness of Nasal Sprays and Allergy Shots: A Battle in the Desert of Allergies

Allergic rhinitis, commonly known as hay fever, can be a real drag, especially during pollen season. This research dives deep into the desert of allergies, comparing two popular treatment approaches: aqueous steroid nasal spray (budesonide) and allergen-injection therapy (Pollinex-R). Using a double-blind, parallel-group trial, researchers put these treatments to the test. They observed that budesonide, like a refreshing oasis in the desert, provided significant relief from nasal symptoms compared to Pollinex-R. This finding is quite interesting, especially when you consider that Pollinex-R injections can cause some unwanted side effects.

Budesonide Nasal Spray: A Breeze in the Desert

The study showed that the budesonide-treated group experienced minimal nasal symptoms and used very little terfenadine, a medication used to manage allergy symptoms. This indicates that the nasal spray is a much more effective and convenient option for treating seasonal allergies compared to allergy shots. The researchers found a statistically significant difference (p less than 0.0001), which is like saying that the difference was like a towering sand dune in the desert - impossible to miss.

A Cool Drink of Water in the Desert: Relief from Allergies

So, what does this mean for you? This study suggests that a nasal spray can provide effective relief from seasonal rhinitis, which is like finding a refreshing oasis in the desert. Since nasal sprays are generally easy to use and carry fewer risks than allergy shots, they might be the preferred option for many people battling allergies. However, remember that everyone's allergies are different, and it is always best to consult with your doctor to find the most effective treatment for your specific needs.

Dr.Camel's Conclusion

This study is a great example of how research can help us find better ways to manage allergies. It's like finding a clear path through the desert, leading to effective treatment options. Budesonide nasal spray shines in the sun, providing a simple and effective solution to allergy woes. While allergy shots still have their place, this research suggests that nasal spray is a fantastic alternative, especially for those looking for a less invasive and more convenient option.

Date :
  1. Date Completed 1990-04-23
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

2107241

DOI: Digital Object Identifier

10.1016/0091-6749(90)90100-i

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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