Comparison of intranasal methamphetamine and d-amphetamine self-administration by humans.

Author: FoltinRichard W, GundersonErik W, HartCarl L, JohansonChris-Ellyn, KirkpatrickMatthew G, LevinFrances R

Paper Details 
Original Abstract of the Article :
AIMS: There are no studies directly comparing self-administration of methamphetamine and d-amphetamine by humans. This study compared intranasal methamphetamine- and d-amphetamine self-administration and characterized the mood, performance and physiological effects produced by the drugs. DESIGN: A ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/22050030

データ提供:米国国立医学図書館(NLM)

Comparing Methamphetamine and d-amphetamine: A Journey Through the Mind

This research delves into the realm of substance abuse, comparing the effects of intranasal methamphetamine and d-amphetamine self-administration in human recreational methamphetamine users. The authors utilize a randomized, double-blind, placebo-controlled, cross-over design, meticulously analyzing the effects of each drug on mood, performance, and physiological measures. The study's findings highlight the remarkable similarities in the effects of methamphetamine and d-amphetamine, suggesting comparable abuse potential. The authors observe that both drugs increase cardiovascular activity and positive mood, while methamphetamine produces more pronounced effects on specific measures like heart rate and feelings of euphoria. This research provides valuable insights into the neuropharmacological underpinnings of drug addiction, offering a deeper understanding of the similarities and differences between these two amphetamines.

The Desert of Addiction: Navigating a Complex Landscape

The research highlights the complex and multifaceted nature of drug addiction. Just as a desert can be both beautiful and dangerous, so too can the pursuit of pleasure through drug use lead to both positive and negative consequences. This research underscores the importance of understanding the neurobiological mechanisms underlying addiction, paving the way for more effective treatment and prevention strategies. By understanding the nuances of drug addiction, we can better navigate the complexities of this challenging landscape and offer support and guidance to those struggling with substance abuse.

The Impact of Drugs on the Mind: A Journey Through the Sands of Time

The study's findings remind us of the profound impact that drugs can have on our minds and bodies. Just as the shifting sands of the desert can obscure our path, so too can drug use distort our perceptions and alter our decision-making processes. This research encourages us to approach drug use with caution and seek help when necessary. By understanding the potential consequences of drug abuse, we can make informed decisions that prioritize our health and well-being.

Dr.Camel's Conclusion

This study underscores the need for a nuanced understanding of the effects of drugs on the mind and body. The similarities between methamphetamine and d-amphetamine in terms of abuse potential highlight the importance of addressing the root causes of addiction and developing effective treatment and prevention strategies.

Date :
  1. Date Completed 2012-05-22
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22050030

DOI: Digital Object Identifier

NIHMS405444

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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