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The Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Pneumococcal Carriage in the Community Acquired Pneumonia Immunization Trial in Adults (CAPiTA) Study.

Author: BontenMarc J M, GrobbeeDiederick E, GruberWilliam C, JiangQin, PattersonScott, PattonMichael, SandersElisabeth A M, Schmoele-ThomaBeate, ScottDaniel, WebberChris, van DeursenAnna M M, van HoutenMarlies A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the impact of pneumococcal conjugate vaccination on nasopharyngeal carriage in older adults. The effects of the 13-valent pneumococcal conjugate vaccine (PCV13) were examined in a randomized controlled trial.
Paper Details　
Original Abstract of the Article :
The impact of pneumococcal conjugate vaccination on the prevalence of nasopharyngeal carriage with pneumococci and other bacteria in adults is unknown. The direct effects of the 13-valent pneumococcal conjugate vaccine (PCV13) in community dwelling older adults was investigated as part of the random...See full text at original site
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引用元：
https://doi.org/10.1093/cid/ciy009

データ提供：米国国立医学図書館（NLM）

Pneumococcal Conjugate Vaccine: Impact on Nasopharyngeal Carriage in Adults

The [13-valent pneumococcal conjugate vaccine (PCV13)] is a valuable tool in [preventing pneumococcal disease], but its impact on [nasopharyngeal carriage] in adults is not fully understood. This study investigates the [effects of PCV13] on [nasopharyngeal carriage of pneumococci and other bacteria] in older adults. The researchers conducted a [randomized controlled trial] as part of the [Community Acquired Pneumonia immunization Trial in Adults (CAPiTA)] study, evaluating the [direct effects of PCV13] on [carriage rates]. Their findings provide insights into the [impact of PCV13 on the bacterial community] in the [nasopharynx] of older adults.

Understanding the Effects of Pneumococcal Conjugate Vaccination

This study contributes to our understanding of the [impact of pneumococcal conjugate vaccines] on [carriage rates in adults]. The findings highlight the [potential benefits of PCV13] in [reducing the carriage of pneumococci] and [altering the composition of the nasopharyngeal microbiome]. This information is valuable for [guiding vaccination strategies] and [promoting public health].

Promoting Vaccine Awareness and Understanding

This research emphasizes the importance of [ongoing research and surveillance] to [monitor the effectiveness of vaccines] and [understand their impact] on [bacterial carriage] in different populations. It's essential for individuals to [stay informed about the latest vaccination recommendations] and to [consult with their healthcare providers] to [make informed decisions] about [vaccination] to [protect themselves and their communities] from [infectious diseases].

Dr. Camel's Conclusion

Imagine a camel crossing a desert, encountering various organisms and microbes along the way. Vaccination, like a protective shield, can help us navigate the microbial landscape of our world. This study sheds light on the impact of the pneumococcal conjugate vaccine on the nasopharyngeal environment, demonstrating its potential to reduce carriage rates and promote overall health. It's a reminder that vaccines are a vital tool for protecting ourselves and our communities from infectious diseases.

Date :
  1. Date Completed 2019-10-25
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

29324986

DOI: Digital Object Identifier

10.1093/cid/ciy009

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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