Review article: long-term safety of oral anti-viral treatment for chronic hepatitis B.

Author: ChanH L-Y, SetoW-K, WongG L-H, WongV W-S, YuenM-F

Paper Details 
Original Abstract of the Article :
BACKGROUND: Safety profile of nucleos(t)ide analogues is an important issue in view of its widespread use for decades in patients with chronic hepatitis B (CHB). AIM: To review and evaluate the latest evidence on the safety profiles of the six approved nucleoside analogues. METHODS: Relevant artic...See full text at original site
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引用元:
https://doi.org/10.1111/apt.14497

データ提供:米国国立医学図書館(NLM)

Long-Term Safety of Oral Antivirals: Navigating the Desert of Hepatitis B

Chronic hepatitis B (CHB) is a persistent viral infection, a challenging desert to navigate for those affected. This review examines the long-term safety of oral antiviral treatment for CHB, focusing on the six approved nucleos(t)ide analogues. It's like studying the long-term impact of a desert's climate on its inhabitants, understanding the potential effects of these antiviral medications over time. The review analyzes the latest evidence on nephrotoxicity, bone toxicity, and other potential adverse effects associated with long-term use. This research is a crucial step in understanding the safety profile of these medications, ensuring the best possible care for CHB patients.

A Balancing Act: Safety and Efficacy

This review provides a comprehensive overview of the long-term safety profile of nucleos(t)ide analogues used in CHB treatment. It's like carefully navigating a desert, ensuring the balance between the benefits of these medications and potential risks. The researchers' findings highlight the importance of regular monitoring and personalized treatment approaches to optimize safety and efficacy. This research is a valuable resource for healthcare providers and patients alike, guiding them through the complex terrain of CHB treatment.

A Journey Through Time: Long-Term Implications

This review underscores the importance of understanding the long-term implications of antiviral treatment for CHB. It's like studying the ancient rock formations in a desert, uncovering the history of this disease and its treatment over time. The researchers' findings highlight the evolving landscape of CHB treatment, demonstrating the need for continued research and innovation to ensure the best possible care for patients. This research is a testament to the ongoing quest for better treatments and improved outcomes for those battling CHB.

Dr. Camel's Conclusion

This review provides a valuable roadmap for navigating the desert of CHB treatment, offering insights into the long-term safety of nucleos(t)ide analogues. The researchers' findings highlight the importance of ongoing research, ensuring safe and effective treatment options for those battling this persistent viral infection. It's like finding a sustainable source of water in the desert, ensuring a healthy and fulfilling journey through the challenges of CHB.

Date :
  1. Date Completed 2019-06-12
  2. Date Revised 2019-06-13
Further Info :

Pubmed ID

29359487

DOI: Digital Object Identifier

10.1111/apt.14497

SNS
PICO Info
in preparation
Languages

English

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