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Oral and sublingual immunotherapy for egg allergy.

Author: CalevoMaria Grazia, RomantsikOlga, ToscaMaria Angela, ZappettiniSimona

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Oral immunotherapy is an effective treatment for egg allergy in children, although it is associated with a high rate of adverse events. Most children receiving oral immunotherapy were able to ingest a partial serving of egg and almost half were able to tolerate a full serving of egg, compared to a minority of control group children. However, nearly all children who received oral immunotherapy experienced adverse events, including serious allergic reactions requiring epinephrine.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. OBJECTIVES: To determine the efficacy and safety of oral and sublingual immunotherapy in c...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494514/

データ提供：米国国立医学図書館（NLM）

Oral and Sublingual Immunotherapy for Egg Allergy: A Promising Treatment Approach

Egg allergy is a common food allergy that can significantly impact an individual's quality of life. Current management relies heavily on strict avoidance of egg-containing foods, but new treatment options are emerging. This systematic review investigates the efficacy and safety of oral and sublingual immunotherapy (OIT and SLIT) for egg allergy in children and adults. The researchers analyzed existing studies comparing OIT or SLIT with placebo or an egg avoidance diet. The review aimed to assess the effectiveness and safety of these immunotherapy approaches. The review found that both OIT and SLIT were effective in increasing the amount of egg that individuals could tolerate. However, these treatments were also associated with frequent adverse events, including allergic reactions, highlighting the importance of careful monitoring and management.

Immunotherapy for Egg Allergy: A Potential Path to Tolerance

The review's findings demonstrate the potential of OIT and SLIT in desensitizing individuals with egg allergy, allowing them to tolerate increasing amounts of egg. However, the frequent occurrence of adverse events underscores the need for careful monitoring and management during these treatments.

Health Implications and Practical Applications

Imagine a desert traveler, cautiously navigating a landscape where certain plants can trigger allergic reactions. Similarly, individuals with egg allergy must navigate a world filled with potential allergens. This review highlights the potential benefits of OIT and SLIT in desensitizing individuals to egg, offering a path towards greater freedom and a wider range of food choices.

Dr.Camel's Conclusion

This systematic review provides valuable insights into the potential of OIT and SLIT in managing egg allergy. While these treatments offer promising opportunities to increase tolerance, the need for careful monitoring and management of adverse events remains a critical consideration.

Date :
  1. Date Completed 2018-05-22
  2. Date Revised 2022-08-13
Further Info :

Pubmed ID

29676439

DOI: Digital Object Identifier

PMC6494514

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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