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Clinical trial comparing timolol ophthalmic solution to pilocarpine in open-angle glaucoma.
Author: BogerW P, Pavan-LangstonD, PuliafitoC A, SteinertR F
Original Abstract of the Article :
A ten-week, double-masked, randomized, clinical trial compared timolol ophthalmic solution and pilocarpine in the therapy of open-angle glaucoma. Timolol decreased the intraocular pressure at least as much as pilocarpine and did not induce miosis, accommodative spasm, or other annoying side effects....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/0002-9394(78)90006-5
データ提供:米国国立医学図書館(NLM)
Timolol vs. Pilocarpine: A Showdown in Open-Angle Glaucoma
Open-angle glaucoma is a serious eye condition that can lead to vision loss if left untreated. This study compared the effectiveness of timolol ophthalmic solution and pilocarpine in managing open-angle glaucoma. The study, a ten-week, double-masked, randomized clinical trial, found that timolol decreased intraocular pressure (IOP) at least as effectively as pilocarpine, without inducing miosis, accommodative spasm, or other bothersome side effects. While timolol did slow the pulse rate, it did not affect blood pressure. Importantly, significant decreases in IOP were still observed after ten weeks of maintenance therapy with the same concentration of the drug.
Timolol: A Promising Treatment for Open-Angle Glaucoma
The study findings suggest that timolol is an effective and well-tolerated treatment for open-angle glaucoma. Timolol demonstrated comparable efficacy to pilocarpine while offering a more favorable side effect profile. This highlights the importance of considering alternative treatment options and carefully evaluating the potential benefits and risks associated with each medication.
Open-Angle Glaucoma: A Silent Thief of Vision
Open-angle glaucoma is often referred to as a silent thief of vision, as it progresses without noticeable symptoms in the early stages. Regular eye exams are crucial for detecting glaucoma early and preserving vision. If you have been diagnosed with open-angle glaucoma, it is essential to follow your healthcare provider's recommendations for treatment and follow-up care.
Dr.Camel's Conclusion
The desert is a harsh environment, just as glaucoma can be a serious threat to vision. This study sheds light on the potential of timolol as an effective treatment for open-angle glaucoma, providing hope for individuals seeking to preserve their vision. Remember, regular eye exams are crucial for early detection and treatment of glaucoma. Like a wise traveler navigating the desert, take care of your vision and consult your healthcare provider for any concerns.
Date :
- Date Completed 1978-09-25
- Date Revised 2019-06-27
Further Info :
Related Literature
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