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Adverse events related to alpha-blockers: analysis of real-life data from Eudra-Vigilance.

Author: BaldassarriValeria, CicioneAntonio, D'AnnunzioSimone, DE NunzioCosimo, FrancoAntonio, GuarnottaGiorgio, LombardoRiccardo, ManciniElisa, NacchiaAntonio, RovestiLorenzo M, TemaGiorgia, TubaroAndrea, VoglinoOlivia A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study analyzed real-life data on neuro-vascular and sexual adverse events (AEs) associated with alpha-blockers (ABs) reported to the Eudra-Vigilance database. The study found that silodosin had a significantly higher risk of ejaculatory disorders, while tamsulosin and silodosin had a lower risk of orthostatic hypotension compared to other ABs.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Patients on alpha-blockers (ABs) treatment may have an increased risk of adverse events (AEs). Aim of our study was to compare real-life data on neuro-vascular and sexual AEs associated with ABs based on Eudra-Vigilance reported AEs. METHODS: Eudra-Vigilance (EV) database is the system ...See full text at original site
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引用元：
https://doi.org/10.23736/S2724-6051.23.05225-4

データ提供：米国国立医学図書館（NLM）

Alpha-Blockers - A Closer Look at Adverse Events

This study analyzes real-life data from Eudra-Vigilance, a system for managing and analyzing suspected adverse reactions to medicines, to compare the risks of adverse events (AEs) associated with different alpha-blockers (ABs). The study finds that certain ABs, like silodosin, are associated with a higher risk of ejaculatory disorders, while others, like tamsulosin, are associated with a lower risk of orthostatic hypotension. This research provides valuable information for clinicians to consider when prescribing ABs.

Navigating the Risks: Alpha-Blockers and Patient Safety

The study reveals that the risks associated with different ABs can vary significantly. This information is crucial for clinicians to consider when prescribing these medications, ensuring that patients are aware of the potential risks and benefits.

Informed Decision-Making: Alpha-Blockers and Personalized Care

This research highlights the importance of personalized care when prescribing medications. Understanding the specific risks and benefits of different ABs can help clinicians make informed decisions about treatment, ensuring that patients receive the most appropriate and safe care.

Dr. Camel's Conclusion

Just as a camel navigates a diverse and challenging desert landscape, clinicians navigate the complex world of medication choices. This study provides valuable insights into the risks associated with different alpha-blockers, reminding us that every medication comes with potential benefits and risks. This research underscores the importance of careful consideration and individualized treatment strategies to ensure patient safety and optimal health outcomes.
Date :
  1. Date Completed 2023-08-03
  2. Date Revised 2023-08-03
Further Info :

Pubmed ID

37067186

DOI: Digital Object Identifier

10.23736/S2724-6051.23.05225-4

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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