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The effect of a once-daily oral dose of nadolol on intraocular pressure in normal volunteers.

Author: RennieI G, SmerdonD L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Nadolol, a beta-blocker, was found to significantly decrease intraocular pressure in healthy volunteers. Both 20 mg and 40 mg doses were effective, with the higher dose providing longer-lasting effects.
Paper Details　
Original Abstract of the Article :
We compared the effects of once-daily oral administration of 20 mg and 40 mg of nadolol vs placebo in 40 normal volunteers in a randomized, double-masked trial. Each of 23 women and 17 men (ranging in age from 18 to 50 years) had intraocular pressure, pulse rate, blood pressure, pupil size, amplitud...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9394(85)90511-2

データ提供：米国国立医学図書館（NLM）

Nadolol: A Desert Oasis for Intraocular Pressure

Glaucoma, a condition that affects the eye's pressure, can feel like navigating a treacherous desert, where the threat of vision loss looms large. This study explores the potential of nadolol, a beta-blocker medication often used to treat high blood pressure, as a treatment for glaucoma, seeking to find a safe and effective oasis in this challenging landscape.

Nadolol: A Refreshing Oasis in the Desert of Glaucoma

The study reveals that nadolol, when administered orally, demonstrates a significant decrease in intraocular pressure, a welcome discovery akin to finding a hidden spring of relief in the desert. This effect, observed at both 20mg and 40mg doses, provides a glimmer of hope for individuals seeking to manage their glaucoma effectively.

Navigating the Desert of Glaucoma: A New Path

This study offers a new perspective on glaucoma management, highlighting the potential of nadolol as a valuable tool for controlling intraocular pressure. The findings encourage further exploration and investigation, seeking to understand the long-term effects and optimize the use of nadolol in treating this complex condition.

Dr.Camel's Conclusion

The desert of glaucoma can be a daunting place, where the risk of vision loss casts a long shadow. This study unveils a potential oasis in the form of nadolol, offering a glimmer of hope for individuals seeking to manage this challenging condition. The findings encourage us to explore new pathways in treating this complex disease, seeking innovative solutions that can create a more peaceful and comfortable journey through this challenging landscape.

Date :
  1. Date Completed 1985-10-21
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

4037034

DOI: Digital Object Identifier

10.1016/0002-9394(85)90511-2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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