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The side effect profile of buspirone in comparison to active controls and placebo.

Author: AlmsD R, BenesC O, CastenG P, MarunyczJ D, NewtonR E

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Buspirone (20 mg) was less sedative and less likely to cause lethargy or depression than diazepam (20 mg) or clorazepate (24 mg). Other side effects were similar to those of benzodiazepines, with nervousness, headache, and dizziness occurring more frequently with buspirone.
Paper Details　
Original Abstract of the Article :
Animal studies and the original study comparing buspirone with diazepam and placebo indicated that sedative-hypnotic side effects and impairment in psychomotor function would be less with buspirone than with diazepam. This was borne out by the present double-blind study in which almost 700 patients ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6130065

データ提供：米国国立医学図書館（NLM）

Buspirone: A Gentle Approach to Anxiety

This research delves into the world of anxiety treatment, comparing the side effect profile of buspirone, an anti-anxiety medication, with active controls and placebo. The study involved almost 700 patients who received either buspirone, diazepam (a benzodiazepine), clorazepate (another benzodiazepine), or placebo. The researchers carefully monitored the patients for various side effects, including sedation, lethargy, depression, and others. This study is significant as it provides insights into the relative safety and tolerability of different medications used to manage anxiety.

Buspirone: A Softer Touch for Anxiety

The study revealed that buspirone was associated with significantly less sedation, lethargy, and depression compared to diazepam or clorazepate, and was comparable to placebo. This suggests that buspirone might be a gentler option for individuals seeking relief from anxiety.

Managing Anxiety: Finding the Right Path

Choosing the right medication for anxiety is a personal journey. It's important to consult with a healthcare professional to determine the best treatment plan for your individual needs and preferences.

Dr.Camel's Conclusion

This research, like a camel navigating a winding desert path, helps us understand the nuances of anxiety treatment. The study highlights the potential benefits of buspirone as a gentler and safer alternative for managing anxiety.

Date :
  1. Date Completed 1983-03-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6130065

DOI: Digital Object Identifier

6130065

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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