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Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood. Pediatric Oncology Group.
Author: CamittaB, CarrollA, ChangM N, Graham-PoleJ, InoueS, KrischerJ, RavindranathY, SteuberC P, WeinsteinH J, YeagerA M
Original Abstract of the Article :
BACKGROUND: The value of autologous bone marrow transplantation in the treatment of children with acute myeloid leukemia (AML) is unknown. We compared autologous bone marrow transplantation with intensive consolidation chemotherapy as treatments for children with AML in first remission. METHODS: We...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1056/NEJM199605303342203
データ提供:米国国立医学図書館(NLM)
Bone Marrow Transplant vs. Intensive Chemotherapy for Childhood AML
Acute myeloid leukemia (AML) is a serious condition, especially for children. This study explores the effectiveness of two treatment approaches for children with AML in first remission: autologous bone marrow transplantation and intensive consolidation chemotherapy. The researchers conducted a [research methodology] to compare the outcomes of these two treatment strategies. It's like navigating a desert with two different paths, each with its own challenges and rewards.
Similar Outcomes for Two Distinct Treatment Approaches
The study found that both autologous bone marrow transplantation and intensive consolidation chemotherapy resulted in similar rates of event-free survival and overall survival at three years. It's like reaching the same oasis, even though the journey was taken on different paths. While the relapse rate was lower in the bone marrow transplant group, there was a higher rate of treatment-related mortality.
Finding the Right Path for Pediatric AML
This research highlights the need for careful consideration when choosing treatment strategies for children with AML. It's like choosing the path that best suits the individual's needs and circumstances. The study emphasizes that the choice of treatment should be based on a thorough assessment of individual factors and potential risks and benefits.
Dr. Camel's Conclusion
This study provides valuable insights into the treatment of childhood AML. It demonstrates that there is not one universally best path, but rather a range of options to consider. The journey through this challenging desert requires careful navigation, considering both the terrain and the individual's needs.
Date :
- Date Completed 1996-06-13
- Date Revised 2022-03-31
Further Info :
English
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