Comparative effects of combination drug therapy regimens commencing with either losartan potassium, an angiotensin II receptor antagonist, or enalapril maleate for the treatment of severe hypertension.

Author: BermanR, GazdickL P, GoldbergA I, RuffD, SweetC S

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare the efficacy and safety of a regimen of losartan potassium (losartan) and a regimen of enalapril maleate (enalapril) in a randomized trial of patients with severe hypertension in which the initial treatments were blinded. DESIGN AND METHODS: Seventy-five patients, 23-74 years ...See full text at original site
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引用元:
https://doi.org/10.1097/00004872-199602000-00017

データ提供:米国国立医学図書館(NLM)

Navigating the High Road: Managing Severe Hypertension

This research is like a camel caravan traversing the vast desert of [hypertension], seeking the most effective path to manage severe hypertension. The authors embarked on a [research method] journey to compare the efficacy and safety of two different drug therapy regimens: one based on losartan potassium and the other on enalapril maleate. They evaluated the impact of these regimens on [purpose] in patients with severe hypertension, like a caravan leader seeking the optimal route through a challenging terrain.

A Tale of Two Regimens

This study provides valuable insights into the effectiveness of different drug therapy regimens for severe hypertension. The researchers found that both losartan-based and enalapril-based regimens effectively lowered blood pressure, though the enalapril regimen showed slightly greater reduction. Both regimens were generally well-tolerated, highlighting the importance of tailoring treatment to individual needs. The study's findings offer a roadmap for healthcare professionals in managing patients with severe hypertension.

Navigating the Desert of Hypertension

This study underscores the importance of choosing the right treatment for managing hypertension. It reminds us that every patient is unique and their journey through the desert of hypertension may require different approaches. The researchers' findings provide valuable guidance for selecting the most effective and safe treatment strategies, ensuring a smoother and more successful journey for patients.

Dr. Camel's Conclusion

This research is a testament to the complexity of managing hypertension. It demonstrates the importance of having multiple tools in our arsenal, like a camel caravan with a diverse collection of supplies, to effectively address this widespread condition. This study provides valuable insights into the effectiveness of different drug therapy regimens, helping us navigate the vast desert of hypertension with more confidence and precision.

Date :
  1. Date Completed 1996-10-01
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

8728306

DOI: Digital Object Identifier

10.1097/00004872-199602000-00017

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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