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Effects of nicotine dose and administration method on withdrawal symptoms and side effects during short-term smoking abstinence.

Author: AickinM, CookG, HillA L, HoldenT, KligmanE, LeischowS J, OtteP S, ValenteS N

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study evaluated the effects of different nicotine replacement treatments on self-reported withdrawal symptoms and side effects during smoking cessation. The 24-hr patch was more effective than the 16-hr patch in reducing morning urge to smoke. Double-patch use resulted in greater insomnia.
Paper Details　
Original Abstract of the Article :
The effects of using several nicotine replacement treatments on self-reported withdrawal symptoms and side effects during 2-day periods of smoking cessation, with 5 days of ad lib smoking between cessation days, were evaluated. Participants (N = 18) experienced the following conditions: nicotine gum...See full text at original site
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引用元：
https://doi.org/10.1037//1064-1297.5.1.54

データ提供：米国国立医学図書館（NLM）

Nicotine Replacement Therapy: A Journey Through Withdrawal Symptoms

The struggle to quit smoking is a desert trek, fraught with challenges and temptations. Nicotine replacement therapy (NRT) is a vital tool in this journey, offering a lifeline to those seeking to break free from tobacco’s grip. This study delves into the effects of different NRT methods on withdrawal symptoms during short-term smoking abstinence, exploring the impact of nicotine dose and administration methods.

The researchers evaluated the effects of various NRTs, including nicotine gum and patches, on self-reported withdrawal symptoms and side effects in 18 participants over two-day periods of smoking cessation. The study found that the 16-hour patch resulted in greater morning urge to smoke compared to the 24-hour patch, highlighting the importance of dose and timing in managing withdrawal symptoms. It also discovered that using a double patch led to significantly more insomnia than the baseline and 16-hour patch conditions, reminding us that NRT can have side effects that need to be managed.

Navigating the Rough Terrain of Nicotine Withdrawal

This study underscores the importance of choosing the right NRT method for individual needs and addressing potential side effects. The findings suggest that while NRT can be an effective tool for managing nicotine withdrawal, it is not a one-size-fits-all solution. It’s like choosing the right camel for your desert journey; each one has its own strengths and weaknesses.

Finding the Right Path to Freedom

The findings of this study provide valuable insights into the complexities of nicotine withdrawal and the role of NRT in managing this challenging process. It’s a reminder that quitting smoking is a personal journey, and the right path to freedom from tobacco may vary depending on individual needs and preferences.

Dr.Camel's Conclusion

This study provides a detailed look into the effectiveness of different NRT methods in managing nicotine withdrawal. It highlights the importance of choosing the right approach and addressing potential side effects. It’s a reminder that while quitting smoking is a difficult journey, with the right tools and support, it is possible to overcome this challenge and create a healthier future.

Date :
  1. Date Completed 1997-09-12
  2. Date Revised 2019-11-02
Further Info :

Pubmed ID

9234040

DOI: Digital Object Identifier

10.1037//1064-1297.5.1.54

SNS
PICO Info
in preparation
Languages

English

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