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Effects of cisapride on symptoms and postcibal small-bowel motor function in patients with irritable bowel syndrome.

Author: CampbellF C, HauC, LoudonM A, NoorN, SmallP K

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effects of long-term treatment with cisapride, a medication that speeds up digestion, on bowel movement and symptoms in patients with irritable bowel syndrome (IBS). The study focused on how cisapride affected the movement of the jejunum (a part of the small intestine) after eating.
Paper Details　
Original Abstract of the Article :
Irritable bowel syndrome is a common cause of abdominal pain and discomfort and may be related to disordered gastrointestinal motility. Our aim was to assess the effects of long-term treatment with a prokinetic agent, cisapride, on postprandial jejunal motility and symptoms in the irritable bowel sy...See full text at original site
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引用元：
https://doi.org/10.1080/00365529850171873

データ提供：米国国立医学図書館（NLM）

Cisapride for Irritable Bowel Syndrome: A Prokinetic Approach in a Turbulent Gut

The study investigates the effects of cisapride, a prokinetic agent, on symptoms and small-bowel motor function in patients with irritable bowel syndrome (IBS). IBS is a common disorder characterized by abdominal pain, discomfort, and altered bowel habits. The researchers aimed to understand how cisapride might improve symptoms and regulate gastrointestinal motility in IBS patients.

Regulating the Gut's Rhythms: Cisapride's Potential

The study explored the potential of cisapride to improve postprandial jejunal motility, a key aspect of gut function. While the study did not provide definitive conclusions about the efficacy of cisapride in IBS, it opened doors for further investigation into the role of prokinetic agents in managing this complex disorder. Imagine a desert traveler experiencing a turbulent sandstorm; cisapride might offer a way to stabilize the gut's internal environment and reduce the impact of the storm.

Managing IBS: A Collaborative Journey

This study underscores the importance of exploring various treatment options for IBS, recognizing that each patient's journey is unique. Consulting with a healthcare professional to discuss potential benefits and risks of cisapride and other treatments is crucial for finding the best approach for managing IBS symptoms. Like navigating a desert with varying terrain, managing IBS requires a personalized approach and ongoing collaboration with healthcare professionals.

Dr. Camel's Conclusion

This study highlights the complexity of IBS and the need for continued research into effective treatment options. Cisapride, a prokinetic agent, shows promise in potentially improving gastrointestinal motility and reducing symptoms, but further investigation is needed to fully understand its role in managing IBS. Just as a desert landscape requires a careful understanding of its diverse terrain, managing IBS demands a personalized approach and a commitment to exploring innovative treatments.
Date :
  1. Date Completed 1998-09-15
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

9669632

DOI: Digital Object Identifier

10.1080/00365529850171873

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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