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A neglected modality in psychiatric treatment--the monoamine oxidase inhibitors.

Author: JohnsonW C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Monoamine oxidase inhibitors (MAOIs) are effective antidepressants when used appropriately, but can cause serious side effects such as toxic hepatocellular damage and hypertensive crises. MAOIs are the therapeutic agents of choice in atypical depressions associated with anxiety, phobic and hysterical symptoms, and depressive illnesses that have failed to respond to tricyclic antidepressants.
Paper Details　
Original Abstract of the Article :
The monoamine oxidase inhibitors are at present being used relatively infrequently in my opinion because of reports of severe and dangerous side effects such as toxic hepatocellular damage and hypertensive crises and also on account of several studies which have not given a very encouraging picture ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1175468

データ提供：米国国立医学図書館（NLM）

Monoamine Oxidase Inhibitors: A Neglected but Powerful Tool in Psychiatry

In the vast landscape of psychiatric treatment, monoamine oxidase inhibitors (MAOIs) have sometimes been overlooked due to concerns about potential side effects. However, this article argues that MAOIs are valuable therapeutic agents when used judiciously. The author challenges the prevailing perception of MAOIs as dangerous, highlighting their effectiveness in treating specific types of depression, particularly those resistant to traditional antidepressants.

The Potential of MAOIs for Atypical and Resistant Depression

The article emphasizes the potential of MAOIs for treating atypical depressions characterized by anxiety, phobic symptoms, and hysterical features. It also suggests that MAOIs can be effective in treating endogenous depressions that have not responded to tricyclic antidepressants. This highlights the importance of considering MAOIs as a viable option when conventional treatments fail to provide adequate relief.

The Importance of Careful Monitoring and Patient Education

The author acknowledges the potential risks associated with MAOIs, such as toxic hepatocellular damage and hypertensive crises. However, he stresses that these risks can be minimized with careful monitoring and patient education. The article emphasizes the importance of avoiding foods high in tyramine content, a crucial factor in preventing potentially dangerous interactions with MAOIs.

Dr.Camel's Conclusion

Much like a camel navigating a treacherous desert, psychiatric treatment requires a careful and informed approach. This article reminds us that MAOIs, despite their historical complexities, offer a valuable tool for treating specific types of depression. With careful monitoring and a commitment to patient education, MAOIs can serve as a vital resource in the journey towards mental well-being.

Date :
  1. Date Completed 1975-12-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1175468

DOI: Digital Object Identifier

1175468

SNS
PICO Info
in preparation
Languages

English

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