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[Effects of amiodarone versus sotalol in treatment of atrial fibrillation: a random controlled clinical study].

Author: ChenYun-xia, GuoWen-ling, HuangCong-xin, JiangHong, JinChun-rong, LiuZhuo-min, NiuFan, YangBo

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Amiodarone is more effective than sotalol in converting atrial fibrillation to sinus rhythm and maintaining sinus rhythm. The adverse reaction of amiodarone on the heart is less severe than that of sotalol.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the effects and adverse reactions of amiodarone and sotalol in treatment of atrial fibrillation. METHODS: One hundred and two patients with atrial fibrillation, 56 males and 46 females, aged 56 +/- 11, were randomized into 2 equal groups: amiodarone group, taking amiodarone 6...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/16620720

データ提供：米国国立医学図書館（NLM）

Comparing Amiodarone and Sotalol for Atrial Fibrillation

The human heart is a complex organ, and keeping its rhythm steady is a crucial part of overall health. Atrial fibrillation (AFib) is a common heart rhythm disorder that can cause a variety of problems. This research aimed to compare the effectiveness of two drugs, amiodarone and sotalol, in treating AFib.

Amiodarone Shows Superiority in Sinus Rhythm Maintenance

The study involved 102 patients with AFib, randomly assigned to receive either amiodarone or sotalol. While both drugs were found to be effective in converting AFib to a normal heart rhythm (sinus rhythm), amiodarone demonstrated a clear advantage in maintaining this rhythm for a longer period. Interestingly, the study also observed a lower rate of serious side effects with amiodarone compared to sotalol. These results suggest that amiodarone may be a more favorable treatment option for AFib patients.

Implications for Heart Health

This research provides valuable insights for managing AFib, a condition that affects millions worldwide. It underscores the importance of carefully considering the potential benefits and risks of different medication options when treating heart rhythm disorders. It's a reminder that finding the right medication for each individual is crucial for effective treatment and improved quality of life.

Dr. Camel's Conclusion

It's like choosing the right camel for a long journey across the desert: just as some camels are better suited for certain terrains, some medications are more effective for specific heart conditions. This research helps us navigate the diverse landscape of heart rhythm disorders and find the best path to better heart health.

Date :
  1. Date Completed 2008-02-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16620720

DOI: Digital Object Identifier

16620720

SNS
PICO Info
in preparation
Languages

Chinese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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