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An evidence based systematic review of remifentanil associated opioid-induced hyperalgesia.

Author: BuckleyMitchell S, CoonsJames C, Kane-GillSandra L, RiceMark J, RivosecchiRyan M, SmithburgerPamela L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Opioid-induced hyperalgesia (OIH) is a concerning side effect of therapeutic opioid use. While opioids are known for their effects on bradycardia and respiratory depression, OIH remains an area of active research to better understand its mechanisms and management.
Paper Details　
Original Abstract of the Article :
Therapeutic opioid use continues to grow, with greater than a fivefold increase in usage of fentanyl-based products over a 10-year period. Opioids are known for their side-effect profile, including bradycardia and respiratory depression; questions remain, however, regarding lesser known side effects...See full text at original site
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引用元：
https://doi.org/10.1517/14740338.2014.902931

データ提供：米国国立医学図書館（NLM）

Understanding Remifentanil-Associated Opioid-Induced Hyperalgesia

This evidence-based systematic review examines the phenomenon of opioid-induced hyperalgesia (OIH) associated with remifentanil, a widely used opioid anesthetic. The review highlights the growing use of opioids and the need to understand the potential risks associated with OIH. While opioids are effective analgesics, they can also lead to hyperalgesia, a condition where pain becomes more intense or prolonged. The review provides a comprehensive overview of the evidence surrounding remifentanil-associated OIH, prompting further research into effective strategies for managing this complication.

Navigating the Opioid Landscape: A Complex Journey

This systematic review provides valuable insights into the complexities of opioid use and the potential for OIH, a significant challenge in pain management. The review highlights the need for a balanced approach to opioid therapy, carefully weighing the benefits against the risks. It's a reminder that, like a camel navigating a desert with limited resources, we must be mindful of the potential consequences of our actions and make informed decisions to ensure the well-being of those entrusted to our care.

Managing Opioid-Related Pain: A Collaborative Effort

As a healthcare professional, I recognize the importance of responsible opioid use and the need to understand the potential risks associated with OIH. This review underscores the importance of ongoing research into effective strategies for managing this complication. It's a reminder that, like a caravan crossing the desert, we must work collaboratively to ensure the safe and effective use of opioids in pain management. This collaborative approach, involving physicians, pharmacists, and patients, is essential for optimizing treatment outcomes and minimizing the risk of OIH.

Dr. Camel's Conclusion

This systematic review provides a comprehensive overview of remifentanil-associated OIH, highlighting the importance of understanding this potential complication and developing effective management strategies. It's a reminder that, like a camel navigating a vast and challenging desert, we must be vigilant and adaptive in our approach to opioid therapy to ensure the safety and well-being of our patients.

Date :
  1. Date Completed 2014-12-09
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24669819

DOI: Digital Object Identifier

10.1517/14740338.2014.902931

SNS
PICO Info
in preparation
Languages

English

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