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Absence of clinically relevant cardiovascular interaction upon add-on of mirabegron or tamsulosin to an established tamsulosin or mirabegron treatment in healthy middle-aged to elderly men.
Author: BrooksAshley, DickinsonJames, DorrepaalCaroline, Gangaram-PandayShanti, KrauwinkelWalter, MeijerJohn, TretterReiner, van GelderenMarcel
Original Abstract of the Article :
OBJECTIVE: Tamsulosin and mirabegron may be used concomitantly in patients with lower urinary tract symptoms. Since alpha1-adrenoceptor antagonists are associated with cardiovascular side effects, potential pharmacokinetic and cardiovascular interactions were evaluated. MATERIALS AND METHODS: This ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.5414/CP201979
データ提供:米国国立医学図書館(NLM)
Mirabegron and Tamsulosin: A Smooth Desert Journey
Pharmacology, like a vast desert landscape, is filled with intricate interactions between different medications. This study investigates the potential cardiovascular interactions between mirabegron and tamsulosin, two medications commonly used for lower urinary tract symptoms. The researchers used a [research methodology] to assess the effects of co-administration of mirabegron and tamsulosin on cardiovascular parameters. The study found that [key findings]. These findings provide reassurance about the cardiovascular safety of co-administering these medications.
Mirabegron and Tamsulosin: A Safe Oasis in the Desert of Medications
This study suggests that co-administering mirabegron and tamsulosin does not pose clinically significant cardiovascular risks. This is good news for patients needing both medications, as they can safely navigate the desert of treatment without worrying about excessive cardiovascular side effects.
Navigating the Desert of Medication Interactions: Patient Guidance
It's always important to discuss your medication regimen with your doctor. Be open and honest about any medications you are taking, including over-the-counter supplements and herbal remedies. This helps ensure your doctor is aware of all potential interactions and can provide you with the safest and most effective treatment plan.
Dr. Camel's Conclusion
This study offers valuable insights into the safety profile of combining mirabegron and tamsulosin. The research, like a well-charted path through a vast desert, provides reassurance about the cardiovascular safety of this combination therapy, allowing patients to navigate their treatment journey with confidence.
Date :
- Date Completed 2014-09-25
- Date Revised 2018-12-02
Further Info :
English
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