Paper Details

  1. Home
  2. Paper Details

Oral and sublingual immunotherapy for egg allergy.

Author: BruschettiniMatteo, CalevoMaria Grazia, Della Casa AlberighiOrnella, RomantsikOlga, ToscaMaria Angela, ZappettiniSimona

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Oral immunotherapy (OIT) for egg allergy was found to be effective in desensitizing a large number of egg-allergic patients. Thirty-nine percent of OIT participants could tolerate a full serving of egg compared to 11.9% of the control group. However, OIT was associated with a high frequency of mild-to-severe adverse effects, with 69% of participants experiencing such effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy (OIT) might be an optional treatment, through desensitization to egg allergen. OBJECTIVES: We aimed to assess the successful desensitization and development of tol...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/14651858.CD010638.pub2

データ提供：米国国立医学図書館（NLM）

Oral and Sublingual Immunotherapy for Egg Allergy: A Comprehensive Review

This review delves into the promising realm of immunotherapy for egg allergy, focusing on oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) as potential treatment options. The authors meticulously analyze the current evidence, including randomized controlled trials (RCTs), to evaluate the efficacy and safety of these therapies in desensitizing patients to egg allergen. Their review reveals that while both OIT and SLIT show promise, more research is needed to establish standardized protocols and optimize treatment strategies for this common food allergy.

Desensitizing to Egg Allergen: A Journey Through Immunotherapy

The review provides a thorough analysis of the available evidence on OIT and SLIT for egg allergy. It indicates that OIT can effectively desensitize a significant proportion of egg-allergic patients, enabling them to tolerate a full or partial serving of egg. While these findings are encouraging, it remains unclear whether long-term tolerance is achieved with OIT. The review also highlights the common occurrence of adverse effects during OIT, though these are usually mild and self-limiting.

Navigating Egg Allergy: A Desert of Dietary Restrictions

Egg allergy can be a challenging condition, impacting daily life. This review underscores the importance of understanding the potential benefits and limitations of OIT and SLIT in managing egg allergy. It emphasizes the need for more research to develop standardized protocols and optimize treatment strategies. It also highlights the importance of close monitoring and careful management of potential adverse effects.

Dr.Camel's Conclusion

This review is a fascinating exploration of the potential benefits of OIT and SLIT in managing egg allergy. Think of it like a journey through a desert, where OIT and SLIT offer potential oases of relief for egg-allergic individuals. While the path to desensitization may not always be smooth, the potential for improved quality of life is significant. More research is needed to ensure that these therapies are safe and effective for all patients.
Date :
  1. Date Completed 2014-12-30
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

25405335

DOI: Digital Object Identifier

10.1002/14651858.CD010638.pub2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.