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Adverse effects reported in the use of gastroesophageal reflux disease treatments in children: a 10 years literature review.

Author: Bueno de MesquitaMirjam, CohenShlomi, MimouniFrancis B

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Gastroesophageal reflux (GER) is common in children, particularly infants. This article reviews the adverse effects of medications used to treat GER in children. The study found that proton pump inhibitors (PPIs) and H2 receptor antagonists (H2 RAs) can cause a number of side effects, including headaches, diarrhea, and nausea.
Paper Details　
Original Abstract of the Article :
Gastroesophageal reflux (GER) is commonly observed in children, particularly during the first year of life. Pharmacological therapy is mostly reserved for symptomatic infants diagnosed with GER disease (GERD), usually as defined in a recent consensus statement. The purpose of the present article was...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541968/

データ提供：米国国立医学図書館（NLM）

Adverse Effects of GERD Treatments in Children

Ah, childhood - a time of endless energy, boundless curiosity, and... gastroesophageal reflux disease (GERD). This study dives into the world of medications used to treat GERD in children, specifically looking at potential side effects. It's like a camel caravan venturing into unfamiliar territory, searching for the safest route.

The authors reviewed 10 years of research, focusing on common GERD medications used in children. They found that adverse effects were reported in at least 23% of patients treated with histamine H2 receptor antagonists (H2 RAs) and 34% of those treated with proton pump inhibitors (PPIs). Common side effects included headaches, diarrhea, nausea (H2 RAs and PPIs), and constipation (PPIs). It's like a camel caravan facing unexpected sandstorms and navigating treacherous terrain.

They also noted a potential risk of lower respiratory tract infections and nosocomial sepsis in immune-deficient infants and children treated with acid-suppressing medications. This is an important consideration, as it highlights the delicate balance of benefits and risks when treating GERD in young patients.

Careful Consideration of GERD Treatments in Children

This study underscores the importance of carefully considering the potential risks and benefits of GERD medications in children. It's like navigating a desert with a compass - we need to understand the potential hazards and choose the safest path.

Understanding the Impact of Medications on Children

The findings of this study are a reminder that medications can have both positive and negative effects on children. It's crucial for healthcare providers to make informed decisions about treatment options, carefully weighing the potential benefits against the risks for each individual child.

Dr.Camel's Conclusion

This study emphasizes the need for careful monitoring and consideration of adverse effects when treating GERD in children. It's like a wise camel guide, reminding us to proceed cautiously, understanding the complexities of the terrain ahead.
Date :
  1. Date Completed 2016-04-18
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

25752807

DOI: Digital Object Identifier

PMC4541968

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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