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Single doses of enalapril and atenolol in hypertensive patients treated with bendrofluazide.

Author: PetrieJ C, RobbO J, WebsterJ, WitteK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Enalapril and atenolol were effective in reducing blood pressure in hypertensive patients already on diuretic treatment. The starting dose of enalapril should be 5 mg, but even this dose may be hazardous in some patients.
Paper Details　
Original Abstract of the Article :
Enalapril in single doses of 5 and 10 mg and atenolol in a single dose of 50 mg were given to 16 hypertensive patients on long-term treatment with bendrofluazide, 5 mg daily, in a double-blind randomized crossover placebo controlled study. Both doses of enalapril and atenolol produced similar effect...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2822797

データ提供：米国国立医学図書館（NLM）

Enalapril and Atenolol: Exploring Single-Dose Effects in Hypertensive Patients

This research examines the effects of single doses of enalapril and atenolol, two common antihypertensive medications, in patients already taking bendrofluazide, a diuretic. The researchers conducted a double-blind randomized crossover study to compare the blood pressure-lowering effects of these medications.

Optimizing Antihypertensive Therapy: Exploring Single-Dose Effects

The study demonstrates that single doses of enalapril and atenolol are effective in lowering blood pressure in patients already receiving diuretic treatment. The findings provide valuable insights into the potential for using single doses of these medications to achieve desired blood pressure control, potentially simplifying medication regimens and improving patient adherence.

Navigating the Desert of Hypertension Management: Finding the Right Path to Control

Managing hypertension requires a multifaceted approach that considers individual patient characteristics and the potential interactions between different medications. This research provides valuable insights into the effects of single-dose antihypertensive medications, highlighting the importance of individualizing treatment plans and carefully monitoring blood pressure responses to different therapies. The findings emphasize the need for a thorough understanding of medication interactions to optimize hypertension management and achieve optimal blood pressure control.

Dr.Camel's Conclusion

This study is like a camel caravan venturing into the desert of hypertension management, seeking the most effective and efficient way to control blood pressure. The researchers have uncovered valuable information about single-dose antihypertensive medications, providing guidance to healthcare professionals and helping patients navigate the path to better blood pressure control.
Date :
  1. Date Completed 1987-12-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2822797

DOI: Digital Object Identifier

2822797

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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