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Cytotoxic effects of neuroleptic drugs.

Author: BrionesD F, MunyonW H, SaloR

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Neuroleptic drugs were found to have varying cytotoxic effects, with thioridazine and chlorpromazine being the most toxic, potentially explaining their higher incidence of agranulocytosis and hepatotoxicity.
Paper Details　
Original Abstract of the Article :
Agranulocytosis and the release of transaminase enzymes from liver cells are known consequences of neuroleptic drug use. These effects are most common with low potency neuroleptic drugs. It has been hypothesized that these effects are due to the direct toxic action of these drugs on blood and liver ...See full text at original site
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引用元：
https://doi.org/10.1007/BF00217059

データ提供：米国国立医学図書館（NLM）

Cytotoxic Effects of Neuroleptic Drugs

Navigating the complexities of the human brain is like traversing a vast desert, filled with intricate pathways and potential pitfalls. This research explores the cytotoxic effects of neuroleptic drugs, examining their potential impact on blood and liver cells. The study uses a series of biological tests to assess the toxicity of various neuroleptic drugs, providing valuable insights into the potential risks associated with these medications.

The authors demonstrate that certain neuroleptic drugs, particularly thioridazine and chlorpromazine, exhibit significant cytotoxic effects. They also highlight the need for careful monitoring and dose adjustments to mitigate these potential risks.

Neuroleptic Drug Toxicity: A Balancing Act

This research underscores the importance of carefully considering the potential cytotoxic effects of neuroleptic drugs. The findings highlight the need for a balanced approach that weighs the therapeutic benefits against the potential risks associated with these medications.

The Importance of Monitoring and Communication

If you are taking a neuroleptic medication, it is crucial to communicate with your healthcare provider about any concerns and to monitor for potential side effects. They can help to ensure that you are receiving the appropriate care and managing your medications safely.

Dr.Camel's Conclusion

The desert of neuroleptic drug therapy can be a treacherous place to navigate, but this research provides valuable insights into the potential risks associated with these medications. It emphasizes the importance of careful monitoring, dose adjustments, and open communication with healthcare providers to ensure safe and effective treatment.

Date :
  1. Date Completed 1987-05-27
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

2883697

DOI: Digital Object Identifier

10.1007/BF00217059

SNS
PICO Info
in preparation
Languages

English

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