Paper Details

  1. Home
  2. Paper Details

Psychotropic effects of enalapril maleate in normal volunteers.

Author: LaderM, OlajideD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Enalapril, an angiotensin-converting enzyme inhibitor, did not have a negative impact on mood in 12 normal subjects. It significantly reduced diastolic blood pressure and increased heart rate, potentially enhancing attention and alertness.
Paper Details　
Original Abstract of the Article :
In order to establish any psychotropic effects of the angiotensin-converting enzyme inhibitor enalapril, the drug was administered in doses of 20 mg every morning for 14 days to 12 normal subjects, and compared with placebo on a battery of physiological, psychological and subjective tests, before an...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/BF00432232

データ提供：米国国立医学図書館（NLM）

Enalapril: A Mind-Boosting Oasis in the Desert of Hypertension

High blood pressure is a common problem, and enalapril is a medication used to treat it. This research explores the potential mental effects of enalapril on healthy individuals. While enalapril is known for lowering blood pressure, this study investigates if it also influences mood, attention, and alertness.

Twelve volunteers took 20mg of enalapril every morning for two weeks. Compared to a placebo group, the participants taking enalapril showed a significant decrease in diastolic blood pressure and an increase in heart rate. Interestingly, the study also found that enalapril increased one component of the brain's response to sound and quickened reaction time. The most common side effect was tiredness.

Enalapril: A Potential Mind-Boosting Oasis

The researchers found that enalapril, unlike many other blood pressure medications, did not lower mood. Instead, it might even enhance attention and alertness.

Navigating the Desert of High Blood Pressure with Enalapril

This research suggests that enalapril, while primarily used to manage high blood pressure, may also have a positive impact on mental function. It's important to note that this study was conducted on healthy volunteers and more research is needed to fully understand the effects of enalapril on those with high blood pressure.

Dr.Camel's Conclusion

Enalapril, like a refreshing oasis in a hot desert, offers a potential benefit for both physical and mental health. While it primarily helps control blood pressure, this research suggests that it might also enhance focus and alertness.

Date :
  1. Date Completed 1985-10-01
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

2994148

DOI: Digital Object Identifier

10.1007/BF00432232

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.