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The impact of pneumococcal conjugate vaccines on serotype 19A nasopharyngeal carriage.

Author: GessnerBradford D, HiltonBetsy, JodarLuis, SchmittHeinz-Josef, SingsHeather L, SyrochkinaMaria, TaysiBulent, Tin Tin HtarMyint

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review assesses the impact of pneumococcal conjugate vaccines (PCVs) containing serotype 19A or cross-reactive 19F on 19A carriage. It finds that PCV13 is more effective in reducing 19A carriage than PCV7 or PCV10, suggesting its importance in areas with high serotype 19A transmission.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>: By preventing nasopharyngeal carriage acquisition among vaccinated persons, and thus reducing transmission, pneumococcal conjugate vaccines (PCVs) provide protection against pneumococcal vaccine serotypes among unvaccinated individuals. This systematic review assessed PCVs cont...See full text at original site
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引用元：
https://doi.org/10.1080/14760584.2019.1675521

データ提供：米国国立医学図書館（NLM）

Pneumococcal Conjugate Vaccines: A Shield Against Serotype 19A Carriage

The world of infectious diseases is a vast desert, filled with microscopic adversaries that constantly threaten our health. This study explores the impact of pneumococcal conjugate vaccines (PCVs) on the carriage of serotype 19A, a specific strain of Streptococcus pneumoniae, a common cause of respiratory infections. It examines the effectiveness of these vaccines in reducing the spread of this potentially harmful bacteria.

Vaccines: A Bastion Against Serotype 19A

This study, based on a comprehensive review of the literature, reveals that PCVs containing serotype 19A or cross-reactive serotype 19F are effective in reducing nasopharyngeal carriage of serotype 19A. While some studies show an increase or no change in carriage with certain PCV formulations, the majority of studies demonstrate a significant decrease in carriage, particularly with PCV13. This finding suggests that PCVs are a valuable tool in preventing the spread of serotype 19A and protecting individuals from pneumococcal infections.

Navigating the Desert of Infectious Diseases

This study highlights the importance of vaccination as a critical shield against infectious diseases. PCVs have proven to be effective in reducing the carriage and spread of serotype 19A, contributing to a healthier population. However, it's essential to continue monitoring the impact of these vaccines and adapting vaccination strategies as needed to address emerging trends in bacterial resistance. The fight against infectious diseases is an ongoing journey through the desert of pathogens, requiring constant vigilance and innovation to protect public health.

Dr. Camel's Conclusion

This study reveals the effectiveness of pneumococcal conjugate vaccines in reducing the carriage of serotype 19A, providing a shield against this potentially harmful bacteria. It underscores the importance of vaccination as a vital tool in navigating the vast desert of infectious diseases and protecting public health. As we continue to explore the intricate world of infectious diseases, vaccines will remain a crucial weapon in our arsenal.

Date :
  1. Date Completed 2020-07-08
  2. Date Revised 2020-07-08
Further Info :

Pubmed ID

31587592

DOI: Digital Object Identifier

10.1080/14760584.2019.1675521

SNS
PICO Info
in preparation
Languages

English

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