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Side effects of minocycline: a double-blind study.

Author: FanningW L, GumpD W, SoffermanR A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Minocycline caused a higher incidence of side effects in women than men. This may be related to higher serum concentrations in women, which could be due to their smaller size.
Paper Details　
Original Abstract of the Article :
We studied the incidence and type of side effects of minocycline in a double-blind study. A total of 45 volunteers (18 men and 27 women) were given minocycline, and 44 volunteers (23 men and 21 women) were given placebo. The men in both the minocycline and placebo groups were significantly (P < 0.00...See full text at original site
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引用元：
https://doi.org/10.1128/AAC.11.4.712

データ提供：米国国立医学図書館（NLM）

Dissecting the Side Effects of Minocycline: A Double-Blind Study

This study delves into the world of antibiotics, specifically investigating the side effects of minocycline. The researchers conducted a double-blind trial, comparing minocycline to a placebo in a group of volunteers. Their findings revealed that minocycline caused a significantly higher incidence of vestibular side effects, particularly in women. The researchers attributed this difference to higher serum concentrations of minocycline in women, potentially related to their smaller size.

Navigating the Minocycline Desert

The research underscores the importance of personalized medicine and the need to carefully consider individual factors when prescribing medications. It's like navigating a desert with a compass – understanding the potential effects of different medications on individuals is crucial for successful exploration. This research highlights the need for vigilant monitoring and individualized treatment approaches, especially for medications like minocycline.

The Importance of Gender-Specific Considerations

This study highlights the importance of considering gender-specific responses to medications. The findings suggest that women may experience a higher incidence of side effects from minocycline, emphasizing the need for careful monitoring and tailored treatment approaches. It's a reminder that just as camels adapt to their unique desert environments, individuals may respond differently to medications based on their individual characteristics.

Dr.Camel's Conclusion

This study provides valuable insights into the side effects of minocycline, particularly emphasizing the higher incidence of vestibular side effects in women. The findings highlight the importance of personalized medicine and gender-specific considerations when prescribing medications. Remember, just like a camel navigates a desert with caution, it's crucial to understand the potential effects of medications on individuals for safe and effective treatment.
Date :
  1. Date Completed 1977-06-22
  2. Date Revised 2021-05-26
Further Info :

Pubmed ID

324400

DOI: Digital Object Identifier

10.1128/AAC.11.4.712

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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