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The Cardiovascular Effects of Newer Antidepressants in Older Adults and Those With or At High Risk for Cardiovascular Diseases.

Author: BehlkeLauren M, CarneyRobert M, LenzeEric J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Depression is a common mental health condition that can affect people of all ages, including older adults. While selective serotonin reuptake inhibitors (SSRIs) are often the first-line treatment for depression, many patients do not respond to these medications. This review summarizes what is known about the cardiovascular side effects of some of the newer antidepressants, including venlafaxine, desvenlafaxine, duloxetine, milnacipran, levomilnacipran, mirtazapine, bupropion, vilazodone, vortioxetine, agomelatine, moclobemide, and ketamine-esketamine. While some of these drugs may be safe and effective alternatives for older adults and patients with cardiovascular disease, more research is needed to fully understand their safety and efficacy in these patient populations.
Paper Details　
Original Abstract of the Article :
Depression is common in older adults and those with cardiovascular disease. Although selective serotonin reuptake inhibitors generally have been shown to be safe to treat depression in these patients, it is important to identify additional antidepressants when selective serotonin reuptake inhibitors...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/33064291

データ提供：米国国立医学図書館（NLM）

Cardiovascular Effects of Newer Antidepressants: Navigating Safety in Older Adults

This research, focused on the

field of geriatric psychiatry and cardiology

, examines the cardiovascular effects of newer antidepressant medications in older adults, particularly those with or at risk for cardiovascular diseases. This narrative review synthesizes existing knowledge on the cardiovascular side effects of 12 novel antidepressants. It analyzes the available research data, outlining the potential risks and benefits associated with each drug, and emphasizing the need for careful administration and close monitoring in vulnerable patient populations.

Navigating the Complexities of Antidepressant Use in Older Adults

The study highlights the importance of careful consideration when prescribing antidepressants to older adults, especially those with pre-existing cardiovascular conditions. It emphasizes the need for individualized treatment plans and thorough monitoring to minimize the risk of cardiovascular complications.

Antidepressants and Cardiovascular Health: A Balancing Act

The study serves as a reminder of the delicate balance between treating depression and mitigating potential cardiovascular risks in older adults. The findings underscore the importance of careful clinical assessment, patient education, and ongoing monitoring in this specific patient population.

Dr. Camel's Conclusion

Like a camel navigating a desert with its unique needs and challenges, older adults with cardiovascular disease need a careful approach to antidepressant therapy. This research provides a roadmap for physicians, helping them navigate the complex terrain of antidepressant use in this vulnerable population.

Date :
  1. Date Completed 2021-10-20
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

33064291

DOI: Digital Object Identifier

NIHMS1638671

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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