Paper Details

  1. Home
  2. Paper Details

Update on Adverse Effects of HIV Integrase Inhibitors.

Author: CailholJohann, CollinsIntira Jeannie, KolakowskaAgnieszka, MarescaAnaenza Freire

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Integrase strand transfer inhibitors (INSTIs) are commonly used to treat HIV infection. This review summarizes recent studies on the neuropsychiatric and weight gain side effects of INSTIs in adults, pregnant women, and children/adolescents.
Paper Details　
Original Abstract of the Article :
The goal of this paper is to provide an up-to-date review of adverse events related to the class of integrase strand transfer inhibitors (INSTIs), which became the class of choice in few years. We sought answers specifically to issues pertaining to neuropsychiatric adverse events, as well as weight ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758219/

データ提供：米国国立医学図書館（NLM）

HIV Integrase Inhibitors: A New Frontier in HIV Treatment

The journey to effectively treat HIV has been marked by significant progress, with the development of new drug classes like integrase strand transfer inhibitors (INSTIs). This paper provides an update on the adverse effects associated with INSTIs, specifically focusing on neuropsychiatric events and weight gain, which have emerged as significant concerns in real-world clinical practice.

Navigating the Side Effects of INSTIs

The paper explores the potential for INSTIs to induce neuropsychiatric adverse events, including mood changes, anxiety, and depression. It also discusses the association between INSTIs and weight gain, a common side effect that can negatively impact quality of life.

Managing HIV Treatment Side Effects

Understanding the potential side effects of INSTIs is crucial for managing HIV treatment effectively. Clinicians need to be aware of these risks and work closely with patients to monitor for any adverse events and adjust treatment strategies accordingly. It's like navigating a desert with potential obstacles along the way, requiring vigilance and adaptability.

Dr.Camel's Conclusion

This paper highlights the importance of continued research and vigilance regarding the potential adverse effects of INSTIs. By understanding these risks and developing effective management strategies, we can ensure that patients receiving INSTIs can benefit from the antiviral efficacy of these medications while minimizing potential complications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

33380904

DOI: Digital Object Identifier

PMC7758219

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.