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Untoward effects of fenfluramine in autistic children.

Author: FreemanB J, GellerE, JensenJ, KlykyloW, PiggottL, RealmutoG M, RitvoE, StubbsG, YuwilerA

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
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Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A double-blind, placebo-controlled cross-over study of 12 children with autism found that fenfluramine was associated with various untoward effects, including listlessness, food refusal, stomach upset, irritability, agitation, and crying. The authors emphasize the importance of understanding fenfluramine's side effects.
Paper Details　
Original Abstract of the Article :
Several recent studies have described the benefits of fenfluramine for the symptomatic treatment of infantile autism. No large surveys of side effects of this drug have been reported in autistic children. To evaluate the untoward effects of fenfluramine in children with autism, 12 subjects were syst...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3543069

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1987-02-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3543069

DOI: Digital Object Identifier

3543069

SNS
PICO Info
in preparation
Languages

English

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