Paper Details
- Home
- Paper Details
Angiotensin converting enzyme during acute and chronic enalapril therapy in essential hypertension.
Author: JacksonB, JohnstonC I
Original Abstract of the Article :
The acute and chronic effects of enalapril (MK421) were assessed in a double-blind randomized trial in subjects with essential hypertension. In acute studies, twelve subjects received enalapril (10 mg p.o.), following which there was a fall in blood pressure, maximal at 6 h and lasting for 24 h. Ser...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1440-1681.1984.tb00278.x
データ提供:米国国立医学図書館(NLM)
Angiotensin Converting Enzyme: A Complex Desert Landscape
The renin-angiotensin system (RAS) plays a vital role in regulating blood pressure and fluid balance in the body. It's like a complex desert ecosystem, with various interconnected elements working together to maintain equilibrium.
This study investigated the effects of enalapril, an angiotensin-converting enzyme (ACE) inhibitor, on blood pressure and ACE activity in patients with essential hypertension. Researchers aimed to understand the [main objective] of enalapril, particularly its acute and chronic effects on the RAS.
The study found that enalapril effectively inhibited ACE activity, leading to a reduction in blood pressure. However, chronic treatment resulted in an induction of ACE, suggesting that the body adapts to long-term ACE inhibition. The key findings include [key findings], highlighting the complex dynamics of the RAS and the need for tailored treatment strategies.
Navigating the Desert of Hypertension
This study provides valuable insights into the complex mechanisms underlying hypertension and the potential benefits of ACE inhibitors like enalapril. It's like understanding the intricate workings of a desert ecosystem and how to manage its resources effectively.
Finding Balance in the Desert of Blood Pressure
This research reminds us that the body's regulatory systems are dynamic and adaptable. It's like navigating a desert landscape, where maintaining balance requires constant adjustments and understanding of the environment.
Dr. Camel's Conclusion
This study underscores the importance of ongoing research into the complex interplay between drugs and the body's regulatory systems. It's like exploring a vast desert, where each discovery leads to a deeper understanding of the intricate mechanisms of life.
Date :
- Date Completed 1985-03-07
- Date Revised 2019-08-25
Further Info :
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.