Paper Details

  1. Home
  2. Paper Details

Drug preference and mood in humans: d-amphetamine.

Author: JohansonC E, UhlenhuthE H

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

This study investigated the subjective effects of d-amphetamine in 31 normal human volunteers. Subjects chose amphetamine a mean of 4.03 times. Amphetamine produced changes in mood, including increased vigor, elation, friendliness, arousal, and positive mood, and decreased confusion.
Paper Details　
Original Abstract of the Article :
A total of 31 normal human volunteers participated in a nine-session experiment. During the first four sessions, they received alternately 5 mg d-amphetamine or placebo. During the next five sessions, they were given a choice between amphetamine and placebo. Subjective effects were assessed using th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/BF00433062

データ提供：米国国立医学図書館（NLM）

Drug Preference and Mood: Exploring the Effects of d-Amphetamine

The study of drug addiction is a complex journey through a vast and often treacherous desert, where understanding the mechanisms of drug reward and dependence is paramount. This research investigates the relationship between drug preference and mood in humans, focusing on the effects of d-amphetamine. The researchers conducted an experiment involving [number of participants], alternately administering d-amphetamine or placebo and assessing mood changes using the Profile of Mood States (POMS). They found that subjects chose d-amphetamine a significant number of times and that d-amphetamine produced specific mood changes, including increased vigor, elation, friendliness, and arousal, and decreased confusion. However, the study found that mood changes did not consistently predict drug choice.

d-Amphetamine: A Complex Relationship with Mood

The study highlights the complex relationship between d-amphetamine and mood. While d-amphetamine can induce mood changes, these changes are not always a reliable predictor of drug preference.

Drug Addiction: A Multifaceted Challenge

Drug addiction is a multifaceted challenge with a complex interplay of biological, psychological, and social factors. This research underscores the importance of understanding the mechanisms of drug reward and dependence to develop more effective prevention and treatment strategies.

Dr.Camel's Conclusion

The desert of drug addiction research is vast and complex. This study provides valuable insights into the relationship between drug preference and mood, highlighting the complex effects of d-amphetamine on human behavior and the need for further research to understand the mechanisms of drug reward and dependence.

Date :
  1. Date Completed 1981-03-27
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

6779335

DOI: Digital Object Identifier

10.1007/BF00433062

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.