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Efficacy of a nicotine nasal spray in smoking cessation: a placebo-controlled, double-blind trial.

Author: DoanK, FranzonM, JarvikM E, ModyF V, OlmsteadR, SchneiderN G, SteinbergC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Nicotine nasal spray (NNS) was significantly more effective than placebo in helping smokers quit. NNS increased success rates at all time points, with 18% of NNS users remaining abstinent after one year.
Paper Details　
Original Abstract of the Article :
Laboratory trials have demonstrated the efficacy of nicotine replacement in smoking cessation but absolute success rates are low. For many, nicotine gum is hard to use and transdermal nicotine is slow-acting and passive. A new, faster-acting nicotine nasal spray (NNS) can provide easily self-adminis...See full text at original site
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引用元：
https://doi.org/10.1046/j.1360-0443.1995.901216719.x

データ提供：米国国立医学図書館（NLM）

Nicotine Nasal Spray: A Viable Option for Smoking Cessation

The fight against smoking is an ongoing battle, with researchers constantly searching for effective ways to help people quit. This study, published in 2007, evaluated the efficacy of a new nicotine nasal spray (NNS) as a smoking cessation aid. This innovative approach aims to provide a faster-acting and more convenient alternative to traditional nicotine replacement therapies.

The researchers conducted a double-blind, placebo-controlled trial involving 255 smokers. They found that NNS significantly enhanced success rates compared to placebo, with a higher proportion of participants achieving continuous abstinence at all test intervals. This suggests that NNS could be a valuable addition to the smoking cessation arsenal. It's like finding a fresh spring in the desert, providing a source of relief and support for smokers looking to quit.

Nicotine Nasal Spray: A Promising Tool in the Fight Against Smoking

The study's findings demonstrate the effectiveness of NNS in promoting smoking cessation. The researchers found that NNS significantly increased success rates compared to placebo, suggesting that it could be a valuable tool in helping smokers quit. The study also highlights the importance of addressing individual needs and preferences when choosing a smoking cessation method, like finding the right path in a vast desert to ensure a safe and successful journey.

Quitting Smoking: A Journey Through the Desert

This research provides valuable insights into the development of smoking cessation therapies. It's like traversing a vast desert, where every new discovery brings us closer to finding a solution to this public health crisis. It's a reminder that even in the face of seemingly insurmountable challenges, progress is possible.

Dr. Camel's Conclusion

The results of this study offer a glimmer of hope for smokers seeking to break free from their addiction. The researchers' findings suggest that NNS could be a viable and effective option for promoting smoking cessation. It's a testament to the power of innovation and the ongoing quest to find solutions for complex health challenges, like finding a hidden oasis in the heart of a vast and unforgiving desert.

Date :
  1. Date Completed 1996-02-28
  2. Date Revised 2019-09-14
Further Info :

Pubmed ID

8555958

DOI: Digital Object Identifier

10.1046/j.1360-0443.1995.901216719.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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