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Short-term side effects of stimulant medication are increased in preschool children with attention-deficit/hyperactivity disorder: a double-blind placebo-controlled study.

Author: BennettS, FirestoneP, MercerJ, MustenL M, PistermanS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Methylphenidate was generally well-tolerated by preschool children with ADHD, with no children withdrawing due to adverse effects. The most common side effects, generally observed at the higher dose (0.5 mg/kg), included decreased appetite, insomnia, and mood changes. Interestingly, some side effects were associated with improved behavior.
Paper Details　
Original Abstract of the Article :
Preschool children with attention-deficit/hyperactivity disorder (ADHD) (27 boys, 5 girls, mean age 4 years 10 months) participated in a double-blind placebo-controlled crossover drug study to assess the side effects of methylphenidate. Children received twice daily, for at least 1 week each, placeb...See full text at original site
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引用元：
https://doi.org/10.1089/cap.1998.8.13

データ提供：米国国立医学図書館（NLM）

Stimulant Medication for ADHD in Preschoolers: Navigating the Sands of Treatment

Attention-deficit/hyperactivity disorder (ADHD), a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity, can be a challenging landscape to navigate, especially in preschool children. This study, like a camel venturing into a new territory, investigates the effects of methylphenidate, a stimulant medication commonly used to treat ADHD, on preschoolers. Researchers conducted a double-blind, placebo-controlled study, evaluating the side effects of methylphenidate in a group of preschool children with ADHD. The study found that methylphenidate was generally well-tolerated, with no children withdrawing due to adverse effects. While some side effects were observed, particularly at higher doses, they were generally not severe, and some were associated with improvements in behavior.

The Desert of ADHD: A Complex Journey

This research provides valuable insights into the use of stimulant medications for ADHD in preschool children, highlighting the need for careful monitoring and individualized treatment approaches. It underscores the importance of considering potential side effects and working closely with healthcare professionals to determine the most appropriate treatment options for individual children.

Navigating the Desert of ADHD

ADHD can have a significant impact on children's development and well-being. Early intervention and support are crucial for helping children manage their symptoms and thrive. Working with a healthcare professional to develop an individualized treatment plan, including medications, behavioral therapies, and educational support, is essential for navigating the desert of ADHD.

Dr. Camel's Conclusion

Methylphenidate, a stimulant medication for ADHD, appears to be relatively well-tolerated in preschool children, but careful monitoring and individualised treatment approaches are crucial. This study, like a camel navigating a complex desert, sheds light on the challenges and potential benefits of this medication, offering insights into managing ADHD in this vulnerable population.
Date :
  1. Date Completed 1998-09-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

9639076

DOI: Digital Object Identifier

10.1089/cap.1998.8.13

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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