Intravenous amiodarone for ventricular arrhythmias: overview and clinical use.

Author: GonzalezE R, KannewurfB S, OrnatoJ P

Paper Details 
Original Abstract of the Article :
Numerous pharmacological agents with varying cellular electrophysiological effects are available to treat cardiac arrhythmias. Amiodarone is predominantly a Vaughan Williams Class III agent, but also possesses electrophysiological characteristics of the other three Vaughan Williams classes (Class I ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/s0300-9572(98)00111-7

データ提供:米国国立医学図書館(NLM)

Intravenous Amiodarone for Ventricular Arrhythmias: Overview and Clinical Use

Numerous pharmacological agents are available to treat cardiac arrhythmias. Amiodarone is a Class III agent, prolonging the cardiac action potential and repolarization time, leading to increased refractory period and reduced membrane excitability. The efficacy and tolerability of intravenous (IV) amiodarone for acute treatment of recurrent and refractory ventricular tachycardia and ventricular fibrillation have been demonstrated in clinical trials. The ARREST trial, comparing IV amiodarone to placebo, found significant improvement in survival to the emergency department following out-of-hospital cardiac arrest in amiodarone-treated patients.

IV Amiodarone: A Powerful Tool for Treating Ventricular Arrhythmias

This research highlights the effectiveness of IV amiodarone for the acute treatment of life-threatening ventricular arrhythmias. The ARREST trial provides compelling evidence supporting its use as an important treatment option for emergency anti-arrhythmic therapy.

Navigating the Desert of Cardiac Arrhythmias

Cardiac arrhythmias can feel like a turbulent desert storm. IV amiodarone, like a sturdy camel, can help navigate these challenging conditions and restore a sense of calm and stability to the heart. This research provides a critical overview of this vital treatment option.

Dr.Camel's Conclusion

This review underscores the effectiveness of IV amiodarone for the acute treatment of life-threatening ventricular arrhythmias. The ARREST trial provides strong evidence for its use as a crucial treatment option in emergency situations. It is a valuable tool for healthcare providers managing cardiac arrhythmias, offering a lifeline in the face of these potentially life-threatening conditions.

Date :
  1. Date Completed 1999-04-14
  2. Date Revised 2019-09-09
Further Info :

Pubmed ID

9918445

DOI: Digital Object Identifier

10.1016/s0300-9572(98)00111-7

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.