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Intravenous amiodarone for ventricular arrhythmias: overview and clinical use.
Author: GonzalezE R, KannewurfB S, OrnatoJ P
Original Abstract of the Article :
Numerous pharmacological agents with varying cellular electrophysiological effects are available to treat cardiac arrhythmias. Amiodarone is predominantly a Vaughan Williams Class III agent, but also possesses electrophysiological characteristics of the other three Vaughan Williams classes (Class I ...See full text at original site
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引用元:
https://doi.org/10.1016/s0300-9572(98)00111-7
データ提供:米国国立医学図書館(NLM)
Intravenous Amiodarone for Ventricular Arrhythmias: Overview and Clinical Use
Numerous pharmacological agents are available to treat cardiac arrhythmias. Amiodarone is a Class III agent, prolonging the cardiac action potential and repolarization time, leading to increased refractory period and reduced membrane excitability. The efficacy and tolerability of intravenous (IV) amiodarone for acute treatment of recurrent and refractory ventricular tachycardia and ventricular fibrillation have been demonstrated in clinical trials. The ARREST trial, comparing IV amiodarone to placebo, found significant improvement in survival to the emergency department following out-of-hospital cardiac arrest in amiodarone-treated patients.
IV Amiodarone: A Powerful Tool for Treating Ventricular Arrhythmias
This research highlights the effectiveness of IV amiodarone for the acute treatment of life-threatening ventricular arrhythmias. The ARREST trial provides compelling evidence supporting its use as an important treatment option for emergency anti-arrhythmic therapy.
Navigating the Desert of Cardiac Arrhythmias
Cardiac arrhythmias can feel like a turbulent desert storm. IV amiodarone, like a sturdy camel, can help navigate these challenging conditions and restore a sense of calm and stability to the heart. This research provides a critical overview of this vital treatment option.
Dr.Camel's Conclusion
This review underscores the effectiveness of IV amiodarone for the acute treatment of life-threatening ventricular arrhythmias. The ARREST trial provides strong evidence for its use as a crucial treatment option in emergency situations. It is a valuable tool for healthcare providers managing cardiac arrhythmias, offering a lifeline in the face of these potentially life-threatening conditions.
Date :
- Date Completed 1999-04-14
- Date Revised 2019-09-09
Further Info :
English
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