Varenicline attenuates some of the subjective and physiological effects of intravenous nicotine in humans.

Author: HermanAryeh I, MooneyMarc, SofuogluMehmet, WatersAndrew J

Paper Details 
Original Abstract of the Article :
Varenicline, a partial nicotinic acetylcholine receptor (nAChR) agonist, is approved for smoking cessation. A few preclinical studies examined the pharmacological effects of varenicline, alone or in combination with nicotine. How varenicline affects the pharmacological effects of pure nicotine has n...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19693492

データ提供:米国国立医学図書館(NLM)

Varenicline's Impact on Nicotine's Effects: A Journey Through the Desert of Addiction

The desert of nicotine addiction is a challenging terrain to navigate. This study examines the impact of varenicline, a medication used to aid smoking cessation, on the effects of nicotine in humans. The authors sought to understand how varenicline, a partial nicotinic acetylcholine receptor (nAChR) agonist, interacts with nicotine to influence its pharmacological effects.

The study, conducted on abstinent smokers, found that varenicline attenuates some of the subjective and physiological effects of intravenous nicotine. These findings suggest that varenicline may influence the way the body responds to nicotine, potentially reducing its rewarding effects and making it easier for smokers to break free from their addiction.

Varenicline: A Potential Tool for Smoking Cessation

This research adds to the growing body of evidence supporting the use of varenicline as an effective aid for smoking cessation. By understanding how varenicline interacts with nicotine, researchers can develop more effective strategies for helping smokers quit.

Navigating the Desert of Nicotine Dependence

This research offers a glimpse into the complex interplay between varenicline and nicotine, providing valuable insights for those struggling with nicotine dependence. The findings suggest that varenicline may be a promising tool for helping smokers overcome their addiction, offering a beacon of hope in the vast desert of nicotine dependence.

Dr.Camel's Conclusion

This study provides valuable insights into the impact of varenicline on nicotine's effects, suggesting that it may be a promising tool for smoking cessation. The findings offer hope for those struggling with nicotine dependence, providing a potential pathway for overcoming this challenging addiction.

Date :
  1. Date Completed 2010-01-14
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19693492

DOI: Digital Object Identifier

NIHMS157279

SNS
PICO Info
in preparation
Languages

English

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