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Changing therapy from timolol to betaxolol. Effect on intraocular pressure in selected patients with glaucoma. Timolol-Betaxolol Study Group.

Author: ClineschmidtC M, KulagaS F, TippingR, VogelR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effects of timolol and betaxolol, both beta-blocker eye drops, in 353 patients with controlled intraocular pressure. Patients switched to betaxolol experienced a significant increase in both ocular side effects (burning/stinging and tearing) and intraocular pressure compared to those who continued on timolol.
Paper Details　
Original Abstract of the Article :
Three hundred fifty-three patients whose intraocular pressure was controlled with a timolol maleate ophthalmic solution were studied. Following a baseline period, half were switched (masked and randomized) to treatment with a betaxolol hydrochloride ophthalmic solution and were followed up for 12 we...See full text at original site
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引用元：
https://doi.org/10.1001/archopht.1989.01070020373038

データ提供：米国国立医学図書館（NLM）

The Timolol-Betaxolol Showdown: A Battle of Glaucoma Treatments

The world of ophthalmology, like a desert landscape, is full of intricate details. This research dives into the effectiveness of two glaucoma medications, timolol and betaxolol, in controlling intraocular pressure. The authors meticulously analyzed the effects of switching from timolol to betaxolol in a group of patients, comparing their intraocular pressure and side effects. It's like observing a delicate balance between two oases, each with its unique benefits and drawbacks.

Betaxolol's Effect on Intraocular Pressure

The study found that switching from timolol to betaxolol resulted in a significant increase in intraocular pressure and ocular side effects. It's like a shift in the desert wind, causing a change in the landscape of the oasis. While betaxolol may offer some advantages, the study indicates that it's crucial to carefully consider the potential drawbacks before switching medications.

Navigating Glaucoma Treatment Options

The study provides valuable insights into the intricacies of glaucoma treatment, highlighting the importance of personalized care and careful medication selection. It's like choosing the right path through a desert, considering the terrain and potential obstacles. The findings emphasize the need for ongoing monitoring and a collaborative approach between patients and their ophthalmologists to ensure optimal management of glaucoma.

Dr.Camel's Conclusion

This research emphasizes the importance of personalized care in ophthalmology. It's like a wise camel guide, choosing the best route through the desert based on individual needs. The study highlights the need for a tailored approach to glaucoma treatment, considering the unique characteristics of each patient and their specific needs.

Date :
  1. Date Completed 1989-10-16
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

2571326

DOI: Digital Object Identifier

10.1001/archopht.1989.01070020373038

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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