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Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials.

Author: BerkDavid R, BoodhooTerry I, BruceSuzanne, Cook-BoldenFran E, DhawanSunil S, ForshaDouglass, GoldMichael H, GreenLawrence J, GuenthnerScott, KaoukhovAlexandre, KempersSteven E, KircikLeon H, MooreAngela, NasirAdnan, ParishJennifer L, RendonMarta I, RichPhoebe, SadickNeil, SchmitzCarsten, Stein-GoldLinda, TschenEduardo, TyringStephen K, WeissRobert A, WerschlerPhilip

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Sarecycline, a narrow-spectrum tetracycline antibiotic, was safe, well tolerated, and effective in patients with moderate to severe acne.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Side effects may limit the use of current tetracycline-class antibiotics for acne. OBJECTIVE: Evaluate the efficacy and safety of once-daily sarecycline, a novel, narrow-spectrum tetracycline-class antibiotic, in moderate to severe acne. METHODS: Patients 9-45 years with moderate to se...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/30235387

データ提供：米国国立医学図書館（NLM）

A New Hope for Acne Sufferers

Acne, a common skin condition, can be a real nuisance. Current treatments, such as tetracycline-class antibiotics, often come with pesky side effects that limit their use. This research introduces a novel antibiotic, sarecycline, designed specifically to combat moderate to severe acne. The researchers conducted two identical phase 3 clinical trials, the gold standard for drug testing, to evaluate sarecycline's efficacy and safety. The results showed that sarecycline was effective in treating moderate to severe acne with fewer side effects than traditional tetracycline antibiotics.

Sarecycline: A Promising Solution for Acne

The results of these clinical trials show that sarecycline is a safe and effective treatment for moderate to severe acne. This promising new drug could offer a better option for acne sufferers who are seeking treatment without experiencing the common side effects associated with other antibiotics. The researchers found that sarecycline achieved significant improvement in acne lesions as early as week 3 of treatment, a good sign that it may provide quicker relief than other acne medications.

Hope for Clear Skin and Fewer Side Effects

Sarecycline's effectiveness in treating acne and its lower incidence of side effects compared to traditional antibiotics is a positive development for acne sufferers. This new treatment option could provide a ray of hope for those struggling with moderate to severe acne, offering a path towards clearer skin with fewer unwanted side effects. As with any medication, it is essential to consult a healthcare professional to determine if sarecycline is the right treatment option for you.

Dr.Camel's Conclusion

Sarecycline, like a cool oasis in a scorching desert, offers a refreshing alternative to traditional acne treatments. Its effectiveness and lower risk of side effects make it a potential game-changer for individuals seeking relief from acne. It's important to remember that all medications have their own unique characteristics and potential benefits and risks. Consulting with a healthcare professional is always the best approach to ensure you receive the most appropriate care.

Date :
  1. Date Completed 2018-12-11
  2. Date Revised 2019-01-11
Further Info :

Pubmed ID

30235387

DOI: Digital Object Identifier

S1545961618P0987X

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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